Schizophrenia and quality of life: a one-year follow-up in four EU countries
© Kovess-Masféty et al; licensee BioMed Central Ltd. 2006
Received: 20 March 2006
Accepted: 19 September 2006
Published: 19 September 2006
This article systematically monitors the quality of life (QOL) of patients with schizophrenia from seven different sites across four European countries: France, Ireland, Portugal and Spain.
A one-year prospective cohort study was carried out. Inclusion criteria for patients were: a clinical lifetime diagnosis of schizophrenia according to ICD-10 (F20) diagnostic criteria for research, age between 18 and 65 years and at least one contact with mental health services in 1993. Data concerning QOL were recorded in seven sites from four countries: France, Portugal, Ireland and Spain, and were obtained using the Baker and Intagliata scale. At baseline, 339 patients answered the QOL questionnaire. At one-year follow-up, Spain could not participate, so only 263 patients were contacted and 219 agreed to take part. QOL was compared across centres by areas and according to a global index. QOL was correlated with presence of clinical and social problems, needs for care and interventions provided during the one-year follow-up.
We did not find any link between gender and QOL. There were some significant differences between centres concerning many items. What is more, these differences were relative: in Lisbon where the lowest level of satisfaction was recorded, people were satisfied with food but highly dissatisfied with finances, whereas in St Etienne, where the highest level of satisfaction was recorded, people were less satisfied with food when they were more satisfied with finances. The evolution in one year among those respondents who took part in the follow-up (excluding the subjects from Granada) showed different patterns depending on the items.
The four countries have different resources and patients live in rather different conditions. However, the main differences as far as their QOL is concerned very much depend on extra-psychiatric variables, principally marital status and income.
This article compares the quality of life of patients with schizophrenia in seven centres in four European countries: France (with centres in Lille, Lyon, La Verrière and St Etienne), Ireland (Dublin), Portugal (Lisbon) and Spain (Granada), and relates this to social and clinical characteristics of patients within their different psychiatric systems.
Indeed, there are large differences between these countries, mainly because of diverse historical backgrounds and the different resources made available for the care of patients with severe mental illness. In addition, the deinstitutionalization process has been implemented at various levels over the last twelve years in most European countries. Consequently, the ratio of psychiatric beds per 1,000 inhabitants remains high in some countries, whereas in others this ratio is low, either because of an effort to decrease it or because of a lack of availability. Moreover, alternatives to long-term hospitalisation such as sheltered housing are diversely developed, and in some countries the absence of such resources forces patients to live in their family's homes. The relationships between in-patient and out-patient care systems and the relationships between the psychiatric system and the primary care system vary substantially. As a result, continuity of care is ensured in varying degrees. It is also worth mentioning that social benefits for people suffering from severe psychiatric disorders vary greatly between countries, and are even totally lacking in some of them.
The broad impact of this diversity on the lives of the severely and persistently mentally ill and the resulting completion of the needs generated by such illnesses pose a particular challenge in the assessment of services for these persons . Relevant outcome areas include psychiatric symptoms, functional status, and access to resources and opportunities, subjective well-being, burden to the family and community safety.
Because of this broad array of relevant outcomes and because of a prevailing concern that outcome assessments should include the patient's perspective, increased attention has been paid over the past decade to the development of patient "quality of life" measurements [2, 3]. Assessment of the quality of life (QOL) is therefore emerging as an important criterion of the performance of services [4–6]. QOL approaches occupy, in a sense, an intermediate position between expert-defined assessments of need and client/user-defined demand. They are planned and used by experts, but often collect information about what the respondents value, want and prefer. QOL has become a valued assessment in those branches of medicine dealing with chronic suffering and disability . QOL has also been largely applied to mental health patients since it embodies concern for patients as people and not just as cases . In particular, QOL has been highly documented for patients with schizophrenia [7–16].
A systematic comparison and evaluation of the QOL of patients and their one-year evolution across some European sites will then bring useful information for planning purpose.
The present paper is based on a subset study on QOL conducted under the umbrella of the European Research Group On Schizophrenia (ERGOS).
In the main study, the patients came from a network of researchers and clinicians in 10 centres, from seven countries: France (with centres in Lille, Lyon, La Verrière and St Etienne), Germany (Mannheim), Ireland (Dublin), the Netherlands (Groningen), Portugal (Lisbon) and Spain (Granada). The study aimed to describe and compare the psychiatric care for a group of patients with chronic schizophrenia in a circumscribed geographical area in each participating country from Southern, Central and Northern Europe . This one-year prospective cohort study included patients with a clinical lifetime diagnosis of schizophrenia according to ICD-10 (F20) diagnostic criteria for research , aged between 18 and 65 years old and who had at least one contact with mental health services during the year before inclusion. The selection of patients was conducted on the basis of the clinical diagnosis, which had to be confirmed by the use of a standardized interview schedule for present state: the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) version 1.0 , which allowed for an assessment of lifetime representative episodes of schizophrenia. Patients were eligible for the study independently of whether they were receiving in- or out-patient care.
The results presented here concern a subset of seven centres from four countries: France, Portugal, Ireland and Spain, which agreed to collect additional data on QOL. As for the main study, the baseline assessment took place as soon as possible after a randomised selection from the list of eligible patients (those who had a lifelong diagnostic of schizophrenia assessed by SCAN) and after written informed consent following ethical committee recommendations. Finally, 419 patients constituted the target population (34 initially selected were not contacted because the required number was completed in that centre). 38 (9.0%) could not be contacted any more after selection, and 45 (10.7%) refused to participate in the study. Then, another 29, who participated in the study, did not complete the QOL assessment. So, the final QOL assessment concerned 339 patients at baseline (80.9% participation rate). At one-year follow-up, Spain could not participate in the QOL assessment, so the remaining eligible patients were 263 and only 219 agreed to take part (83.3% of the baseline population).
There are many QOL measures, which can be divided into generic and non generic. Since severe disorders are concerned we thought that a specific measure was needed and we selected the Satisfaction with Life Domains Scale (SLDS) [20, 21]. This scale has the advantage of being one of the shortest QOL measures covering a variety of areas whilst allowing for a global score.
The SLDS was initially developed to evaluate the impact of the Community Support Program in New York State on the QOL of chronically mentally ill patients. It is a self-report scale administered by a trained interviewer and takes approximately 10 minutes to administer. Its individual items cover 15 areas of everyday life: satisfaction with housing, neighbourhood, food, clothing, health, people lived with, friends, family, relations with other people, work/day schedule, spare time, leisure time, services and facilities in the area, economic situation, and place lived in now compared with state hospital. Respondents chose for each area one face from among seven proposed, corresponding to different emotional states. The faces varied from very satisfied and happy to not satisfied at all and sad. These can be summed into a total life satisfaction score.
The SLDS has been extensively used with severe psychiatric patients in Belgium, Quebec and France. The French translation was available to us through a validation study conducted in Quebec . This study allowed ensuring test-retest reliability, internal consistencies and discriminating power when translated in another language. On the other hand, the Spanish and Portuguese translations were done by bilingual experts from this field.
It has to be noted that the initial 15-item version of the SLDS was modified by C. Mercier and P. Corten who deleted 1 item (i.e., place lived in now compared with state hospital) and added 6 items covering love life, freedom and empowerment aspects. This modified version (20 items) was used by all centres except the Irish ones, which used the original 15-item version. Consequently, all results will be presented on the 14 common items for all centres, plus on the 6 added questions except for Dublin.
For the patients who did not answer some of the items of the QOL questionnaire, we attributed the value 4 (medium value) to the items in question in order to be able to compute the global score. Another solution would have been to use the mean or median value found for each item, however significance tests revealed that results would not have differed. For individual item comparisons, we are producing the number of patients by item.
The information concerning sociodemographic variables was collected by the Past History and Sociodemographic Description schedule (PHSD) , which provides information on the level of education, occupational situation, where the patient lives and information on his/her family. Given the variability in educational systems and standards of living across European countries, we had to slightly modify this instrument in order to harmonise the response scales for educational level, professional training and level of income (level of income and existence of a mandatory minimal wage, housing, social benefit based or regular income, variation in the level of attribution of social benefits for patients with schizophrenia according to the different national regulations).
The presence of a significant problem in various clinical and social domains was assessed at entry and followed up through the Needs For Care Assessment Schedule (NFCAS), a standardised procedure created by Brewin [24, 25], which was designed to improve care planning for such patients and has been extensively used in various circumstances [26–28]. A specific inter-rater reliability study was set up to ensure that the standardised training procedures succeeded in obtaining an acceptable level of comparability across countries .
The interview also covered 11 areas of clinical functioning (psychotic symptoms, negative symptoms, side effects of medication, neurotic symptoms, dementia, physical problems, dangerous behaviour, socially embarrassing behaviour, distress, alcohol and drug use) and 11 areas of social functioning (personal hygiene, shopping, getting meals, household chores, use of public transport, use of public amenities, education, occupation, communication, finances and management of own affairs).
The Chi-square test, or the Fisher-exact test, whenever the number of cases was below 5, was used to compare ratios and the Student or Fisher test was used to compare means. In addition, multiple linear regression was used to measure the effect of variables on the level of global satisfaction. The software was SPSS V11 and Epi Info V6. Statistical significance was set at 0.05.
Characteristics of patient populations at entry for seven study areas in four countries
Number of patients
≤ 35 years
Mean age at 1st contact with services
Never married (%)
Sheltered accommodation* (%)
Private accommodation (%)
Regular wages (%)
On social benefit or pension (%)
On average, levels of satisfaction for each area vary from 5.37 for food to 3.77 for finances. Between these extremes, the areas where people are most satisfied are clothing (5.11), housing (5.03), people they live with (5.02); then come family (4.92), neighbourhood (4.83), local services (4.79), relations with others (4.70) and friends (4.59), followed by work or day schedule (4.41), spare time (4.35), health (4.31) and leisure (4.26). If the six newly added items are considered, love life is the area where people are least satisfied (3.69), whereas the one where they are most satisfied is freedom (4.90), followed by responsibilities (4.65), self-confidence (4.41), life in general (4.24) and what other people think of you (4.21).
When comparing variations of total QOL score according to the diverse sociodemographic characteristics for the entire sample at baseline, there are very few significant differences, and ones only relating to income source (p = 0.035): individuals who receive financial assistance from a partner (72.6) or their parents (68.9) are the most satisfied, followed by those who have a salary (67.8), then come those who receive unemployment benefit or social benefit (66.9), followed by those who receive disability benefits for sickness or handicap (65.7), which is the most frequent situation (129/329 cases). The persons least satisfied are those who receive their money for subsistence either from pensions (64.5), extended family or friends (60.7) and other sources of income (57.6).
Evolution in one year
Sociodemographic and environmental variables appear to play a more important role at one-year follow-up than at baseline: with the time passing, their influence on various aspects of QOL increases.
Women's global satisfaction increases (+5.39), whereas men change only slightly (+0.92) over time (p = 0.028). Respondents who are divorced or separated (+10.8) or cohabiting (+8.28) have the highest increase (p = 0.057). Those with the lowest income progress most (+4.58) whereas, in contrast, those with the highest income decline most (-4.33; p = 0.046). Globally, the main areas subject to change over time are finances, which gains one point in each centre, and family relationship, which looses more than one point. All remaining satisfaction areas slightly increase except that of love life which decreases.
These evolutions are sometimes different by centres or according to some of the sociodemographic variables.
Satisfaction with health increases over time in all centres, except La Verrière and St Etienne where it declines (p = 0.009). Relationship with the family deteriorates over time in varying degrees (p = 0.012) in each centre (the greatest deterioration occurring in La Verrière), whereas relationship with friends improves slightly, except in Lisbon (p = 0.038), and relationship with others improves slightly, except in St Etienne (p = 0.017). Leisure improves greatly in La Verrière and in Dublin and deteriorates in St Etienne (p = 0.002).
Compared with men, women improve better their satisfaction with health (p = 0.006) and finances (p = 0.011). Respondents aged over 35 years are more satisfied at one-year follow-up with their responsibilities (p = 0.046). Income level does not appear to have a significant influence in the evolution of satisfaction except concerning local services, which is lower at one-year follow-up for everyone, excluding persons with the minimum legal wage level (p = 0.002). The same group shows also better improvement of their satisfaction concerning the opinion of others (p = 0.048) and the wealthiest improve better in terms of satisfaction about their life in general (p = 0.050). Respondents with the lowest level of education show better improvement compared with the others in terms of health satisfaction (p = 0.044). Those who live in semi-private accommodation experience increase better their satisfaction concerning their housing, unlike those living in private homes or who are homeless (p = 0.036). Satisfaction concerning relations with others change over time: the homeless improve whereas those living in sheltered accommodation deteriorate (p = 0.023). Finally, satisfaction regarding relationship with the family deteriorates, especially in the category of the divorced, separated and never-married (p = 0.000), however, satisfaction with health is better for those divorced whilst it remains unchanged for the others (p = 0.032). Global satisfaction with housing slightly increases for everyone except for those married or widowed (p = 0.038).
At baseline, no variables are found to influence the global satisfaction in a multiple regression analysis using the variables that show significant influences: centre and income level. However, when a multiple regression is conducted on the variables which have an influence on a one-year evolution of global satisfaction namely: centre, gender, income and marital status, the latter remains significant and all other influences disappear.
Frequency of individual ongoing symptoms at inclusion (%)
N = 47*
N = 45
N = 27
N = 50
N = 64
N = 50
N = 84
Side effects. dyskinesia
Factors influencing differences between one-year follow-up and baseline are rather different: the only symptom which influences the global satisfaction score is dangerous behaviour (p = 0.06) and it is at a level that is only just significant.
Most of the differences concerning the various sociodemographic variables appeared at one-year follow-up when some patients had left and one of the centres was missing. Consequently, the differences should be interpreted with caution since the drop-out rate could be due to many reasons linked to the health status of the person. However, it is worth noting that we found no difference in baseline satisfaction between respondents and non-respondents at one-year follow-up, except in Lyon (p = 0.008) where non-respondents at one-year follow-up were associated with greater satisfaction at inclusion.
In addition, it should be noted that all patients included had to be at least once in contact with a specialised mental health care system during the year of inclusion. This excludes those who were in remission as well as those who did not have access to specialised care and unfortunately, we are not able to check any differences. Table 2, which reports their clinical needs, illustrates that at the time of evaluation these patients were highly symptomatic and few of them were homeless, reflecting a relative adequacy of the studied population.
As with the majority of QOL research in both general and mentally ill populations [30–34], we did not find any link between gender and QOL. This result could also be compared with the Vandiver  study on QOL, gender and schizophrenia in the United States, Canada and Cuba which reported greater QOL and satisfaction with social relationships for females in Canada, the reverse with the Cuban sample and no difference between genders in the United States. However, our study shows differences by sex in evolution over one year as in the study of individuals with severe mental illness, conducted by Roder-Wanner, Oliver and Priebe , which found that QOL predictors differed according to gender and gave support to the existence of gender-specific processes and contexts of subjective evaluation.
We did not find many differences between young and old patients, but we did find one concerning finances, which was in favour of the older respondents as in the case with most QOL studies done among the general population and the mentally ill, which found that the older the population the more satisfied they are with their QOL, particularly in the area of finances [33, 34, 37].
Living conditions, such as living arrangements, have been found to impact on the subjective QOL of individuals with severe mental illness. In all studies, the least restrictive living arrangements were associated with better QOL [34, 38, 39]. In our study, we did not find many differences except in relations with friends and the perception of the opinion of others, but we failed to find any difference in satisfaction regarding freedom or responsibilities.
A study by Fabian  showed that, while there was no significant difference between the working and non-working groups on the basis of work status alone, gender appeared to mediate the relationship between employment and QOL indicators. As predicted, working males were the most satisfied group and non-working males the least satisfied. However, working females expressed less satisfaction across all subjective life domains studied than did non-working females. In our study, those who declared they were working were not more satisfied than those persons who were helped by their spouse or parents, but they were more satisfied than pensioners or people living on disability benefits.
Most of the epidemiological research to date has systematically found increased well-being and mental health in people with higher levels of education [35, 41]. However, we found completely inverse results, which fit in with C. Mercier's theory about satisfaction and expectation in which the more educated have higher aspirations leading to a greater distance between where they are and where they would like to be and resulting in their feeling more dissatisfied than people with a lower level of education .
Global comparisons by centres may also reflect the global resources provided to those suffering from severe mental health disorders. In a similar attempt to compare diverse centres in diverse countries, Gaite et al  state that contrary to what has been claimed QOL measures reflect more subjective measures than environmental conditions. Some of their findings are in favour of an accurate relation to environment. In our data, the Lisbon patients' dissatisfaction with finances reflects their environmental situation as well as their high dissatisfaction with services, leisure and friends since most of them were living within their families with no outside resources at all.
Finally, according to the evolution over a one-year period, marital status appears to be one of the most important variables in terms of satisfaction in many areas, as shown in the work of Salokangas and colleagues , which found greater satisfaction in its follow-up among women and married men. The results of Salokangas's studies strongly emphasise that relations between gender, marital status and QOL to a great extent depend on the study sample and may vary by study area.
This study replicates many previous findings, however, its originality stems from the variety of EU countries where the patients were treated: these countries have quite different resources, medical as well as social, and the living conditions of patients are very different. However, the main differences as far as their QOL is concerned depend very much on extra-psychiatric variables, principally marital status and income and not so much on clinical variables.
Concerns of patients are very similar to those of the non patient populations and income is a serious concern: finances and relationships with others, including love life, are the areas where they are the most dissatisfied.
QOL integrates many dimensions and this work shows that an improvement in an area may raise problems in another: for example, being in sheltered housing increases satisfaction with housing but at the same time seems to deteriorate the relationship with others while making no difference in remaining areas.
Globally, with largely different resources, after one year spent under the diverse psychiatric care systems, the patients' satisfaction with finances increases, which may indicate some efficiency on the part of psychiatric teams in gathering subsidies for them. However, satisfying relationships with others including love life are a far more difficult goal to reach for such patients with chronic schizophrenia who experience considerable handicaps in those areas essential for their own conception of QOL.
Quality of Life
International Classification of Diseases
Schedules for Clinical Assessment in Neuropsychiatry
Satisfaction with Life Domains Scale
Past History and Sociodemographic Description schedule
Needs For Care Assessment Schedule
This paper is based on the work of clinicians and research workers who participated in the European study on the evaluation of comprehensive care for patients with schizophrenia:
France: Lille:Dr. Roelandt, Ms. Bruynooghe, Mr. Demoor, Mr. Joignant, Mr. Marien, Dr. Sentchev-Gomes; Lyon:Dr. Dubuis, Ms Duchamp, Dr. Gillet, Ms. Graglia, Mr. Houver, Mr Monier, Dr. Parriaud, Dr. Stallioni, Ms Schnitter, Mr. Roustand, Dr. Suttet; La Verrière : Dr. Lacalmontie, Ms. Dutrut, Dr. Pecot; Saint Etienne: Pr. Pellet, Dr. Bouvy, Ms. Guyon, Ms. Hairwassers, Mr. Jullien, Pr. Lang, Ms. Poyet, Ms. Sert, Mr. Ziegler
Ireland: Dublin:Dr. Walsh, Dr. Daly, Ms. Finnerty, Ms. Keogh, Dr. Lane, Dr. Murphy, Dr. O'Grady-Walsh
Portugal: Lisbon:Dr. Caldas de Almeida, Dr. Coutinho, Dr. E. Martins, Dr. R. Martins, Dr. Xavier
Spain: Granada:Dr. Torres-Gonzalez, Dr. Benítez, Dr. Domínguez, Dr. Jiménez, Dr. Martín, Dr. Moreno, Dr. Pérez
In most centres, the research was made possible by grants from local or national organisations, and was conducted with the support of the psychiatric services. The co-ordination of this multi-centre study was done in Paris, successively by A. Caria, G. Poirier and P. Thiam under the supervision of V. Kovess and with the financial support in the form of a grant from Eli Lilly.
- Brazier JE, Harper R, Jones NM, O'Cathain A, Thomas KJ, Usherwood T, Westlake L: Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ. 1992, 305: 160-164.PubMed CentralView ArticlePubMed
- Maguire P, Selby P: Assessing quality of life in cancer patients. Br J Cancer. 1989, 60: 437-440.PubMed CentralView ArticlePubMed
- Orley J, Saxena S, Herrman H: Quality of life and mental illness. Reflections from the perspective of the WHOQOL. Br J Psychiatry. 1998, 172: 291-293.View ArticlePubMed
- McDowell MI, Newell C: Measuring health: A guide to rating scales and questionnaires. 1987, New York, Oxford University Press
- Thompson NM, Scott DF, Cesnik B, Hooke D, Wood C, Marshall V, Atkins RC: Morbidity, mortality, and quality of life in long-term survivors of an integrated dialysis/renal transplant programme. Transplant Proc. 1989, 21: 2184-2185.
- Oliver D: The quality of care and symptom control--the effects on the terminal phase of ALS/MND. J Neurol Sci. 1996, 139 Suppl: 134-136. 10.1016/0022-510X(96)00087-1.View ArticlePubMed
- Bobes J, Garcia-Portilla P, Saiz PA, Bascaran T, Bousono M: Quality of life measures in schizophrenia. Eur Psychiatry. 2005, 20 Suppl 3: S313-7. 10.1016/S0924-9338(05)80182-8.View ArticlePubMed
- Test MA, Greenberg JS, Long JD, Brekke JS, Burke SS: Construct validity of a measure of subjective satisfaction with life of adults with serious mental illness. Psychiatr Serv. 2005, 56: 292-300. 10.1176/appi.ps.56.3.292.View ArticlePubMed
- Duno R, Pousa E, Domenech C, Diez A, Ruiz A, Guillamat R: Subjective quality of life in schizophrenic outpatients in a Catalan urban site. J Nerv Ment Dis. 2001, 189: 685-690. 10.1097/00005053-200110000-00005.View ArticlePubMed
- Fitzgerald PB, de Castella AR, Filia K, Collins J, Brewer K, Williams CL, Davey P, Kulkarni J: A longitudinal study of patient- and observer-rated quality of life in schizophrenia. Psychiatry Res. 2003, 119: 55-62. 10.1016/S0165-1781(03)00099-4.View ArticlePubMed
- Ritsner M: Predicting changes in domain-specific quality of life of schizophrenia patients. J Nerv Ment Dis. 2003, 191: 287-294. 10.1097/00005053-200305000-00003.PubMed
- Picardi A, Rucci P, de Girolamo G, Santone G, Borsetti G, Morosini P: The quality of life of the mentally ill living in residential facilities : Findings from a national survey in Italy. Eur Arch Psychiatry Clin Neurosci. 2006
- Ritsner M, Gibel A, Ratner Y: Determinants of changes in perceived quality of life in the course of schizophrenia. Qual Life Res. 2006, 15: 515-526. 10.1007/s11136-005-2808-9.View ArticlePubMed
- Malla A, Williams R, Kopala L, Smith G, Talling D, Balshaw R: Outcome on quality of life in a Canadian national sample of patients with schizophrenia and related psychotic disorders. Acta Psychiatr Scand Suppl. 2006, 22-28. 10.1111/j.1600-0447.2006.00758.x.
- de Souza LA, Coutinho ES: The quality of life of people with schizophrenia living in community in Rio de Janeiro, Brazil. Soc Psychiatry Psychiatr Epidemiol. 2006, 41: 347-356. 10.1007/s00127-006-0042-6.View ArticlePubMed
- van de Willige G, Wiersma D, Nienhuis FJ, Jenner JA: Changes in quality of life in chronic psychiatric patients: a comparison between EuroQol (EQ-5D) and WHOQoL. Qual Life Res. 2005, 14: 441-451. 10.1007/s11136-004-0689-y.View ArticlePubMed
- Kovess V, Wiersma D, Caldas de Almeida JM, Carta MG, Dubuis J, Lacalmontie E, Pellet J, Roelandt JL, Salize HJ, Torres-Gonzalez F, Walsh D: Evolution of needs for schizophrenic patients in seven European countries. Psychiatr Netw. 2000, 3: 26-40.
- World Health Organization: The ICD-10 classification of mental and behavioural disorders. Diagnostic criteria for research. 1993, Geneva, World Health Organization
- Wing JK, Babor T, Brugha T, Burke J, Cooper JE, Giel R, Jablenski A, Regier D, Sartorius N: SCAN. Schedules for Clinical Assessment in Neuropsychiatry. Arch Gen Psychiatry. 1990, 47: 589-593.View ArticlePubMed
- Baker F, Intagliata J: Quality of life in the evaluation of community support systems. Eval Program Plann. 1982, 5: 69-79. 10.1016/0149-7189(82)90059-3.View ArticlePubMed
- Lehman AF: Measures of quality of life among persons with severe and persistent mental disorders. Mental health outcome measures. Edited by: Thornicroft G and Tansella M. 1996, Berlin, Springer-Verlag, 75-92.View Article
- Caron J, Mercier C, Tempier R: [Validation of Satisfaction with Life Domains Scale in Quebec]. Sante Ment Que. 1997, 22: 195-217.View ArticlePubMed
- World Health Organization: The international pilot study of schizophrenia. 1973, Geneva, World Health Organization
- Brewin CR, Wing JK, Mangen SP, Brugha TS, MacCarthy B: Principles and practice of measuring needs in the long-term mentally ill: the MRC needs for care assessment. Psychol Med. 1987, 17: 971-981.View ArticlePubMed
- Brewin CR, Wing JK: Manual of the MRC needs for care assessment memo. 1989, London, MRC Social Psychiatry Unit
- van Haaster I, Lesage AD, Cyr M, Toupin J: Further reliability and validity studies of a procedure to assess the needs for care of the chronically mentally ill. Psychol Med. 1994, 24: 215-222.View ArticlePubMed
- Lesage AD, Mignolli G, Faccincani C, Tansella M: Standardized assessment of the needs for care in a cohort of patients with schizophrenic psychoses. Psychol Med Monogr Suppl. 1995, 191: 27-41.
- Wiersma D, Nienhuis FJ, Giel R, de Jong A, Slooff CJ: Assessment of the need for care 15 years after onset of a Dutch cohort of patients with schizophrenia, and an international comparison. Soc Psychiatry Psychiatr Epidemiol. 1996, 31: 114-121. 10.1007/BF00785757.View ArticlePubMed
- Wiersma D: Reliability of the "Needs for Care Assessment Schedule" in a European context: an international comparison. 1996, Groningen, Department of Social Psychiatry, University of Groningen
- Andrews FM, Withey SB: Social indicators of well-being. 1976, New York, Plenum PressView Article
- Campbell A, Converse PE, Rogers WL: The quality of American life. 1976, New York, Russell Sage Foundation
- Diener E: Subjective well-being. Psychol Bull. 1984, 95: 542-575. 10.1037/0033-2909.95.3.542.View ArticlePubMed
- Mercier C, Peladeau N, Tempier R: Age, gender and quality of life. Community Ment Health J. 1998, 34: 487-500. 10.1023/A:1018790429573.View ArticlePubMed
- Kearns RA, Taylor SM, Dear M: Coping and satisfaction among the chronically mentally disabled. Can J Commun Ment Health. 1987, 6: 13-25.View Article
- Vandiver VL: Quality of life, gender and schizophrenia: a cross-national survey in Canada, Cuba, and U.S.A. Community Ment Health J. 1998, 34: 501-511. 10.1023/A:1018742513643.View ArticlePubMed
- Roder-Wanner UU, Oliver JP, Priebe S: Does quality of life differ in schizophrenic women and men? An empirical study. Int J Soc Psychiatry. 1997, 43: 129-143.View ArticlePubMed
- Lehman AF, Slaughter JG, Meyers CP: Quality of life experiences of the chronically mentally ill. Gender and stages of life effects. Eval Program Plann. 1992, 15: 7-12. 10.1016/0149-7189(92)90055-Y.View Article
- Lehman AF, Possidente S, Hawker F: The quality of life of chronic patients in a state hospital and in community residences. Hosp Community Psychiatry. 1986, 37: 901-907.PubMed
- Warner R, Huxley P: Psychopathology and quality of life among mentally ill patients in the community. British and US samples compared. Br J Psychiatry. 1993, 163: 505-509.View ArticlePubMed
- Fabian ES: Work and the quality of life. Psychosoc Rehabil J. 1989, 12: 39-49.View Article
- Dohrenwend BP, Dohrenwend BS: Social status and psychological disorders: a causal inquiry. 1969, New York, Wiley
- Mercier C: Conditions de vie et lieux de résidence. Sante Ment Que. 1989, XIV: 158-171.View Article
- Gaite L, Vazquez-Barquero JL, Borra C, Ballesteros J, Schene A, Welcher B, Thornicroft G, Becker T, Ruggeri M, Herran A: Quality of life in patients with schizophrenia in five European countries: the EPSILON study. Acta Psychiatr Scand. 2002, 105: 283-292. 10.1034/j.1600-0447.2002.1169.x.View ArticlePubMed
- Salokangas RK, Honkonen T, Stengard E, Koivisto AM: To be or not to be married--that is the question of quality of life in men with schizophrenia. Soc Psychiatry Psychiatr Epidemiol. 2001, 36: 381-390. 10.1007/s001270170028.View ArticlePubMed
- The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-244X/6/39/prepub
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