Figure 2
From: Model-based parametric study of frontostriatal abnormalities in schizophrenia patients
Dependences of the striatal activity, X s , and the normalized DA release, Y , on PFC activity, X p . The D2 effects become larger for higher values of b, the coefficient representing the presynaptic depression of the frontostriatal glutamatergic neurotransmission by D2 receptor activation.