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Table 2 Effect of the type of antipsychotic treatment on the evolution of cognitive performance (repeated measures analysis)

From: The switch from conventional to atypical antipsychotic treatment should not be based exclusively on the presence of cognitive deficits. A pilot study in individuals with schizophrenia

 

Conventional APD

Atypical APD

F

P

 

T1

T2

T1

T2

  
 

Mean

SD

Mean

SD

Mean

SD

Mean

SD

  

Digit Span forward

5.58

1.11

5.16

0.98

5.92

1.29

5.30

1.22

0.014

0.906

Digit Span Backwards

3.42

0.95

3.58

0.75

3.92

1.67

3.76

1.24

0.601

0.443

WCST categories

3.15

1.72

3.75

1.92

4.15

2.46

4.46

2.12

0.155

0.697

WCST total errors

62.61

18.82

49.83

22.90

41.23

33.28

35.53

30.20

0.024

0.879

WCST perseverative errors

35.00

14.14

25.75

14.39

22.65

23.20

17.07

16.11

0.095

0.760

FAS Test

39.07

9.84

44.69

9.04

40.11

12.66

48.80

14.68

2.586

0.117

CIG Test

22.07

6.60

29.69

10.75

26.53

16.54

31.84

17.68

0.296

0.590

Trail Making part A

48.50

23.24

47.36

24.51

65.53

56.77

63.10

55.47

0.176

0.677

Trail Making part B

207.00

88.39

148.46

64.67

140.57

63.77

127.46

67.00

0.912

0.346

Digit Symbol

40.30

15.16

43.00

18.18

46.42

16.14

47.92

15.88

0.000

0.988

Stroop Color-Word trial (Interference)

86.53

28.13

66.43

17.35

79.73

42.13

71.11

35.21

0.054

0.818

Babcock Story Recall Test, Immediate memory

5.43

2.25

7.43

2.62

7.90

3.42

8.30

3.83

0.602

0.444

Babcock Story Recall Test, Delayed Recall

8.71

3.45

9.78

3.32

9.63

4.81

10.05

5.17

0.037

0.849

Rey Figure, Immediate

11.38

7.10

16.80

3.76

14.48

7.76

17.21

7.71

2.354

0.120

Rey Figure, 20 min

12.46

6.14

16.36

4.08

14.42

7.97

16.92

7.87

2.533

0.120

Finger-Tapping Test, Unimanual Left Motor Performance

53.69

10.57

57.38

16.28

58.15

21.09

66.80

12.66

1.489

0.231

Finger-Tapping Test, Unimanual Right Motor Performance

61.15

15.15

62.46

24.03

73.61

20.98

77.63

23.38

0.730

0.399

Finger-Tapping Test, Bimanual Left Motor Performance

52.92

12.02

54.07

16.13

60.80

19.93

66.75

19.21

0.113

0.739

Finger-Tapping Test, Bimanual Right Motor Performance

58.92

12.12

54.07

16.13

65.15

21.00

65.52

19.02

1.174

0.286

  1. APD: Antipsychotic drug; DS: Standard Deviation; WCST: Wisconsin Card Sorting Test; CIG Test: Category Instant Generation Test.