Table 1 Summary of Study Designs
From: The potential role of appetite in predicting weight changes during treatment with olanzapine
| Â | Study 1 | Study 2 | Study 3 | Study 4 |
|---|---|---|---|---|
Patient age (years) | 18 to 65 | 18 to 65 | 18 to 65 | ≥ 18 |
Study design | Double-blind | Double-blind | Open-label | Observational |
Olanzapine dose (mg) | 5 to 20 mg QD | 5 to 20 mg QD | 5 to 20 mg QD | Determined by the investigator |
Adjunctive pharmacotherpay | no | no | no or Amantadine 100 mg BID or Metformin 500 mg BID | no |
Appetite assessment scale | Eating Behavior Assessment | Platypus Appetite Rating Scale | Eating Inventory and Food Craving Inventory | Eating Attitude Scale |
Dietary counseling | yes | no | yes | no |
Study length (weeks) | 12 | 16 | 22 | 24 |