Skip to main content

Table 4 Self-reported medication side effects of patients (N = 423)* according to treatment type

From: The cross-sectional GRAS sample: A comprehensive phenotypical data collection of schizophrenic patients

 

FGA1

SGA2

 

men

women

men

women

Parkinson symptoms

17%

15.6%

3.8%

11.6%

dyskinetic/dystonic symptoms

35.8%

31.3%

9.4%

9.7%

akathisia

22.6%

12.5%

6%

6.8%

hyperprolactinaemia

-

-

-

1.9%

hormonal dysfunctions (gynecomastia, absence/changes of menorrhea)

-

9.4%

-

5.8%

sexual dysfunction

7.5%

-

10.3%

-

vertigo (incl. hypotonia)

5.7%

12.5%

5.1%

8.7%

weight gain

9.4%

18.7%

38.3%

39.8%

diabetes mellitus

-

-

0.4%

-

sialorrhea ('drooling')

-

-

20.4%

6.8%

skin abnormalities, loss of hair

1.9%

-

1.7%

5.8%

gastrointestinal symptoms

1.9%

6.3%

5.9%

7.8%

hyperhidrosis

-

-

2.6%

-

psychological symptoms (loss of concentration, no drive, tiredness)

33.9%

28.1%

44.2%

31.1%

cardiovascular symptoms (tachycardia, hypertension)

-

-

1.3%

1.9%

impaired vision

-

-

1.7%

3.9%

dry mouth

5.7%

9.4%

5.1%

4.9%

urinary retention

-

3.1%

1.3%

-

number of patients who reported side effects

53

32

235

103

  1. 1FGA - first generation antipsychotics, typical antipsychotics
  2. 2SGA - second generation antipsychotics, atypical antipsychotics
  3. *Only N = 423 patients (out of 1012 patients who were on antipsychotic medication) reported side effects (see text for details).