Decreased glutathione levels and impaired antioxidant enzyme activities in drug-naive first-episode schizophrenic patients

Table 2 The activities of the RBC antioxidant enzymes in the study groups

Antioxidant enzymes	Patients (N = 23)	Controls (N = 45)	p-values
SOD (U/mg Hb)
Mean ± SD	2.2 ± 0.6	2.4 ± 0.6	0.2
Min-Max	1.5-3.8	1.7-4.6
GPx (U/gHb)
Mean ± SD	68.6 ± 13.5	41.1 ± 26.3	< 0.001*
Min-Max	28.2-122.6	22.9-70.7
CAT (U/gHb)
Mean ± SD	212.2 ± 36.9	284.6 ± 88.2	< 0.001*
Min-Max	157.3-282.5	100.3-499.3

CAT: catalase, GPx: glutathione peroxidase, Max: maximum, Min: minimum, RBC: red blood cell, SD: standard deviation, SOD: superoxide dismutase.
*Adjusted by smoking habit

ISSN: 1471-244X