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Table 1 Overview of assessments and instruments

From: Cocaine Addiction Treatments to improve Control and reduce Harm (CATCH): New Pharmacological Treatment Options for Crack-Cocaine Dependence in the Netherlands

Assessments (researchers)

Baseline

Week 4•

Week 8•

Week 12

Checklist inclusion criteria (control and experimental)

•

   

CIDI - Substance Abuse Module (cocaine& heroine& alcohol)

•

   

MINI - Suicidal risk

•

   

Addiction Severity Index + supplement1

•

   

Addiction Severity Index; short version substance use + supplement1

 

•

•

•

Time Line Follow-Back (cocaine)

•

•

•

•

Maudsley Addiction Profile (MAP) - HSS

•

•

•

•

Symptom Check List- 90 (SCL-90)

•

•

•

•

Obsessive Compulsive Drug Use Scale (OCDUS)

•

•

•

•

Client Satisfaction Questionnaire- 8 (CSQ-8) + supplement2

   

•

Evaluation (control and experimental)

   

•

Medical assessment (physician)

Baseline

Week 4 •

Week 8 •

Week 12

Checklist exclusion criteria (control and experimental)

•

   

First informed consent (control and experimental)

•

   

Second informed consent (only experimental)

•

   

Medical assessment: ECG (only dexamphetamine study)

•

  

•

Medical assessment: blood analysis (week 12 only experimental)

•

  

•

Medical screening: heart rate, blood pressure3 (only experimental)

•

• • • •

• • • •

• • • •

Pregnancy (only experimental; only women)

•

•

•

•

(Serious) adverse events (only experimental)

•

• • • •

• • • •

• • • •

Drug accountability (only dexamphetamine study)

 

• • • •

• • • •

• • • •

Urinalysis cocaine- metabolites (control and experimental; obtained by research assistant)

•

  

• • • •

Treatment participation (consumption of care; medication) (control and experimental)

 

• • • •

• • • •

• • • •

  1. Note. • The assessments in week 4 and 8 are only for participants in the experimental groups (topiramate, modafinil, dexamphetamine SR), 1 The ASI-supplement concerns illegal activities, income, and living arrangements, 2 Additional questions about the treatment(s), 3 In the dexamphetamine study, blood pressure and heart rate will be assessed every day during the first four weeks, • • • • Indicates weekly (instead of monthly) registration.