Skip to main content

Table 3 Logistic regression of factors associated with at least one prescription of cholinesterase inhibitors in the incidence year and characteristics of ChEI users vs.non-users

From: Impact of geriatric comorbidity and polypharmacy on cholinesterase inhibitors prescribing in dementia

Characteristics

ChEI users

(n = 241)

Non-users

(n = 1,607)

Proportion of ChEI user

(n = 1,848)

Model 1a)

ORcrude (95% CI)

Model 2b)

ORadj (95% CI)

Age groups, in years

     

   65-74

107 (44.4%)

459 (28.6%)

18.9%

3.32 (2.13-5.18)

1.41 (0.85-2.34)

   75-84

107 (44.4%)

763 (47.5%)

12.3%

2.00 (1.29-3.10)

1.30 (0.81-2.11)

   85+

27 (11.2%)

385 (24.0%)

6.6%

1

1

Sex

     

   Male

137 (56.8%)

832 (51.8%)

14.1%

1.23 (0.93-1.61)

0.89 (0.65-1.21)

   Female

104 (43.2%)

775 (48.2%)

11.8%

1

1

Area of residence*

     

   Urban

168 (69.7%)

1161 (72.3%)

12.6%

1

1

   Rural

73 (30.3%)

444 (27.7%)

14.1%

1.14 (0.85-1.53)

1.48 (1.06-2.06)

Number of prescribed medications

   Q1 (0-6)

90 (37.3%)

520 (32.4%)

14.8%

1.43 (0.97-2.10)

0.93 (0.58-1.49)

   Q2 (7-9)

59 (24.5%)

352 (21.9%)

14.4%

1.38 (0.91-2.10)

1.03 (0.64-1.65)

   Q3 (10-13)

48 (19.9%)

372 (23.1%)

11.4%

1.06 (0.69-1.64)

0.79 (0.49-1.28)

   Q4 (14+)

44 (18.3%)

363 (22.6%)

10.8%

1

1

Level of care dependency

   None

161 (66.8%)

866 (53.9%)

15.7%

5.83 (1.82-18.61)

5.35 (1.61-17.81)

   1

41 (17.0%)

341 (21.2%)

10.7%

3.77 (1.14-12.44)

4.32 (1.26-14.75)

   2

36 (14.9%)

306 (19.0%)

10.5%

3.69 (1.11-12.24)

3.97 (1.16-13.60)

   3

3 (1.2%)

94 (5.8%)

3.1%

1

1

Symptom complexes characterizing geriatric patients

   0

33 (13.7%)

115 (7.2%)

22.3%

3.46 (1.87-6.41)

4.23 (2.06-8.69)

   1-2

120 (49.8%)

707 (44.0%)

14.5%

2.05 (1.22-3.44)

2.52 (1.41-4.50)

   3-4

70 (29.0%)

568 (35.3%)

11.0%

1.49 (0.87-2.55)

1.59 (0.89-2.84)

   5+

18 (7.5%)

217 (13.5%)

7.7%

1

1

Contacts to neurologists/psychiatrists

   0

43 (17.8%)

981 (61.0%)

4.2%

1

1

   1-2

16 (6.6%)

151 (9.4%)

9.6%

2.42 (1.33-4.40)

2.53 (1.37-4.65)

   3-5

44 (18.3%)

137 (8.5%)

24.3%

7.33 (4.64-11.57)

7.86 (4.88-12.66)

   6-9

84 (34.9%)

141 (8.8%)

37.3%

13.59 (9.04-20.43)

14.05 (9.14-21.59)

   10+

54 (22.4%)

197 (12.3%)

21.5%

6.25 (4.07-9.60)

7.66 (4.85-12.11)

  1. a) crude models
  2. b) multivariate model adjusted for all other variables
  3. * missing values for 2 patients for which classification into the urban or rural group was not possible
Back to article page

BMC Psychiatry

ISSN: 1471-244X

Contact us