Table 5 Baseline Demographics and Illness Severity for Predicted Outcome Groups
Likely Responders | Likely Non-responders | Not Predictable | p-valuea | |
|---|---|---|---|---|
n (%) | 445/1494 (29.8) | 929/1494 (62.2) | 120/1494 (8.0) | |
Age in years, mean (SD) | 39.1 (11.1) | 40.4 (10.6) | 38.9 (10.4) | .06 |
Female gender, n (%) | 167 (37.5) | 295 (31.8) | 51 (42.5) | .02 |
Ethnicity/Race, n (%) | ||||
White | 219 (49.2) | 474 (51.0) | 56 (46.7) | .53 |
Black | 141 (31.7) | 309 (33.3) | 43 (35.8) | |
Hispanic | 85 (19.1) | 146 (15.7) | 21 (17.5) | |
Diagnosis, n (%) | ||||
Schizophrenia | 345 (77.5) | 743 (80.0) | 101 (84.2) | .26 |
Schizoaffective disorder | 95 (21.3) | 186 (20.0) | 18 (15.0) | .31 |
Schizophreniform disorder | 5 (1.1) | 0 (0.0) | 1 (0.8) | .003 |
Age at illness onset in years, mean (SD) | 23.8 (8.8) | 23.4 (8.3) | 23.0 (7.4) | .53 |
Duration of illness in years, mean (SD) | 15.3 (10.9) | 17.0 (10.7) | 15.9 (10.5) | .02 |
Number of prior episodes, median | 5 | 6 | 5 | |
PANSS Total score, mean (SD) | 101.5 (16.1) | 95.4 (14.0) | 101.9 (17.3) | <.001 |
PANSS Positive score, mean (SD) | 25.6 (5.1) | 23.5 (4.2) | 26.1 (4.7) | <.001 |
PANSS Negative score, mean (SD) | 26.0 (5.9) | 24.9 (5.5) | 25.4 (6.0) | .002 |
CGI-S score, mean (SD) | 4.8 (0.8) | 4.7 (0.7) | 4.8 (0.7) | <.001 |
Weight in kg, mean (SD) | 83.0 (22.9) | 84.9 (20.5) | 82.6 (22.0) | .24 |