Reduced antioxidant defense in early onset first-episode psychosis: a case-control study

BMC Psychiatry

Table 3 Oxidative stress variables for patients in the different diagnostic groups versus the control group

	N	Mean	SD	U Mann-hitney	p	N	Mean	SD	U Mann-Whitney	p
	TAS (mM)					GSH (μM)
Control group	94	1.26	0.05			93	394.11	15.90
SCH_b	49	0.91	0.04	1193.50	< 0.001	43	308.34	20.06	1317.50	0.005
PNOS-_a	25	0.99	0.09	622	0.002	21	327.62	29.21	555	0.195
BIP_d	18	0.88	0.06	290.50	0.001	17	347.44	24.15	530.50	0.606
DEP_c	10	1.16	0.14	232.50	0.501	9	350.27	45.23	245.50	0.841
	LOOH (μM)					cGPX (mU/mL)
Control group	82	6.17	0.47			93	912.96	59.93
SCH_b	33	10.06	2.50	1431	0.161	43	1068.37	61.63	2283.50	0.015
PNOS-_a	17	6.03	0.87	641	0.856	21	620.73	135.46	823.50	0.734
BIP_d	15	10.88	1.58	713.50	0.004	17	1142.08	112.88	831	0.031
DEP_c	9	8.82	1.60	328.50	0.083	9	728.812	80.62	228	0.447

_aPNOS: Psychotic disorder not otherwise specified, _bSCH: Schizophrenia spectrum disorder, _cDEP: Depressive disorder with psychotic symptoms, _dBIP: Psychotic bipolar disorder.

ISSN: 1471-244X