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Table 1 Hazard ratios for mortality (36-60 years) by psychiatric disorder at 36 years, obtained from Cox's proportional hazards models and based on 3283 men and women and 204 deaths,

From: Psychiatric disorder in early adulthood and risk of premature mortality in the 1946 British Birth Cohort

   Hazard ratios (95%CI) Test for trend P value
   Male Female All (sex adjusted)  
Unadjusted results
Psychiatric disorder - index of definition** 1 1.0 1.0 1.0 <0.001
  2 1.66 (1.02, 2.70) 1.92 (1.04, 3.57) 1.75 (1.19, 2.56)  
  3 - 7 1.84 (1.05, 3.22) 2.24 (1.22, 4.11) 2.00 (1.34, 3.00)  
   Adjusted for father's social class at 4 years*
Psychiatric disorder - index of definition** 1 1.0 1.0 1.0 <0.001
  2 1.64 (1.01, 2.67) 1.96 (1.05, 3.66) 1.74 (1.19, 2.54)  
  3 - 7 1.82 (1.04, 3.19) 2.20 (1.20, 4.05) 1.97 (1.32, 2.95)  
   Adjusted for IQ at 15 years*
Psychiatric disorder - index of definition** 1 1.0 1.0 1.0 <0.001
  2 1.67 (1.03, 2.73) 1.97 (1.06, 3.66) 1.78 (1.21, 2.60)  
  3 - 7 1.80 (1.02, 3.18) 2.26 (1.22, 4.16) 1.99 (1.33, 2.99)  
Adjusted for educational qualifications by 26 years*
Psychiatric disorder - index of definition** 1 1.0 1.0 1.0 <0.001
  2 1.67 (1.02, 2.73) 1.98 (1.07, 3.66) 1.78 (1.22, 2.62)  
  3 - 7 1.88 (1.07, 3.29) 2.24 (1.22, 4.11) 2.04 (1.36, 3.06)  
Adjusted for social class at 26 years*
Psychiatric disorder - index of definition** 1 1.0 1.0 1.0 <0.001
  2 1.71 (1.05, 2.79) 1.97 (1.06, 3.66) 1.80 (1.23, 2.64)  
  3 - 7 1.93 (1.10, 3.40) 2.20 (1.20, 4.04) 2.04 (1.36, 3.06)  
   Adjusted for social class, IQ, Education and adult social class at 26 years
Psychiatric disorder - index of definition** 1 1.0 1.0 1.0 <0.001
  2 1.70 (1.03, 2.80) 1.95 (1.05, 3.61) 1.80 (1.23, 2.65)  
  3 - 7 1.86 (1.05, 3.29) 2.11 (1.15, 3.88) 2.00 (1.33, 3.00)  
   Adjusted for smoking up to 36 years*
Psychiatric disorder - index of definition** 1 1.0 1.0 1.0 0.001
  2 1.68 (1.02, 2.76) 1.99 (1.07, 3.69) 1.75 (1.19, 2.56)  
  3-7 1.81 (1.03, 3.16) 2.01 (1.07, 3.75) 1.90 (1.26, 2.86)  
   Adjusted for alcohol consumption at 36 years*
Psychiatric disorder - index of definition** 1 1.0 1.0 1.0 <0.001
  2 1.68 (1.03, 2.74) 1.90 (1.02, 3.55) 1.75 (1.19, 2.57)  
  3 - 7 1.93 (1.11, 3.38) 2.20 (1.20, 4.04) 2.02 (1.35, 3.01)  
   Adjusted for physical health status at 36 years *
Psychiatric disorder - index of definition** 1 1.0 1.0 1.0 0.001
  2 1.59 (0.98, 2.58) 1.99 (1.08, 3.65) 1.72 (1.18, 2.51)  
  3 - 7 1.70 (0.96, 3.01) 2.19 (1.19, 4.01) 1.87 (1.25, 2.81)  
Adjusted for all
Psychiatric disorder - index of definition** 1 1.0 1.0 1.0 0.001
  2 1.70 (1.02, 2.83) 2.16 (1.15, 4.02) 1.77 (1.20, 2.61)  
  3 - 7 1.80 (1.01, 3.22) 2.03 (1.09, 3.75) 1.84 (1.22, 2.78)  
  1. * missing data for father's social class (n = 254), IQ at 15 years (n = 462), educational qualifications by 26 years (n = 149), alcohol consumption at 36 years (n = 864), social class at 26 years (n = 225), smoking up to 36 years (n = 251) and physical health status at 36 years (n-61)
  2. ** Index of definition: 1 = no symptoms; 2 = 1-4 symptoms; 3-7 = 5 or more symptoms