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Table 1 Hazard ratios for mortality (36-60 years) by psychiatric disorder at 36 years, obtained from Cox's proportional hazards models and based on 3283 men and women and 204 deaths,

From: Psychiatric disorder in early adulthood and risk of premature mortality in the 1946 British Birth Cohort

  

Hazard ratios (95%CI)

Test for trend P value

  

Male

Female

All (sex adjusted)

 

Unadjusted results

Psychiatric disorder - index of definition**

1

1.0

1.0

1.0

<0.001

 

2

1.66 (1.02, 2.70)

1.92 (1.04, 3.57)

1.75 (1.19, 2.56)

 
 

3 - 7

1.84 (1.05, 3.22)

2.24 (1.22, 4.11)

2.00 (1.34, 3.00)

 

   Adjusted for father's social class at 4 years*

Psychiatric disorder - index of definition**

1

1.0

1.0

1.0

<0.001

 

2

1.64 (1.01, 2.67)

1.96 (1.05, 3.66)

1.74 (1.19, 2.54)

 
 

3 - 7

1.82 (1.04, 3.19)

2.20 (1.20, 4.05)

1.97 (1.32, 2.95)

 

   Adjusted for IQ at 15 years*

Psychiatric disorder - index of definition**

1

1.0

1.0

1.0

<0.001

 

2

1.67 (1.03, 2.73)

1.97 (1.06, 3.66)

1.78 (1.21, 2.60)

 
 

3 - 7

1.80 (1.02, 3.18)

2.26 (1.22, 4.16)

1.99 (1.33, 2.99)

 

Adjusted for educational qualifications by 26 years*

Psychiatric disorder - index of definition**

1

1.0

1.0

1.0

<0.001

 

2

1.67 (1.02, 2.73)

1.98 (1.07, 3.66)

1.78 (1.22, 2.62)

 
 

3 - 7

1.88 (1.07, 3.29)

2.24 (1.22, 4.11)

2.04 (1.36, 3.06)

 

Adjusted for social class at 26 years*

Psychiatric disorder - index of definition**

1

1.0

1.0

1.0

<0.001

 

2

1.71 (1.05, 2.79)

1.97 (1.06, 3.66)

1.80 (1.23, 2.64)

 
 

3 - 7

1.93 (1.10, 3.40)

2.20 (1.20, 4.04)

2.04 (1.36, 3.06)

 

   Adjusted for social class, IQ, Education and adult social class at 26 years

Psychiatric disorder - index of definition**

1

1.0

1.0

1.0

<0.001

 

2

1.70 (1.03, 2.80)

1.95 (1.05, 3.61)

1.80 (1.23, 2.65)

 
 

3 - 7

1.86 (1.05, 3.29)

2.11 (1.15, 3.88)

2.00 (1.33, 3.00)

 

   Adjusted for smoking up to 36 years*

Psychiatric disorder - index of definition**

1

1.0

1.0

1.0

0.001

 

2

1.68 (1.02, 2.76)

1.99 (1.07, 3.69)

1.75 (1.19, 2.56)

 
 

3-7

1.81 (1.03, 3.16)

2.01 (1.07, 3.75)

1.90 (1.26, 2.86)

 

   Adjusted for alcohol consumption at 36 years*

Psychiatric disorder - index of definition**

1

1.0

1.0

1.0

<0.001

 

2

1.68 (1.03, 2.74)

1.90 (1.02, 3.55)

1.75 (1.19, 2.57)

 
 

3 - 7

1.93 (1.11, 3.38)

2.20 (1.20, 4.04)

2.02 (1.35, 3.01)

 

   Adjusted for physical health status at 36 years *

Psychiatric disorder - index of definition**

1

1.0

1.0

1.0

0.001

 

2

1.59 (0.98, 2.58)

1.99 (1.08, 3.65)

1.72 (1.18, 2.51)

 
 

3 - 7

1.70 (0.96, 3.01)

2.19 (1.19, 4.01)

1.87 (1.25, 2.81)

 

Adjusted for all

Psychiatric disorder - index of definition**

1

1.0

1.0

1.0

0.001

 

2

1.70 (1.02, 2.83)

2.16 (1.15, 4.02)

1.77 (1.20, 2.61)

 
 

3 - 7

1.80 (1.01, 3.22)

2.03 (1.09, 3.75)

1.84 (1.22, 2.78)

 
  1. * missing data for father's social class (n = 254), IQ at 15 years (n = 462), educational qualifications by 26 years (n = 149), alcohol consumption at 36 years (n = 864), social class at 26 years (n = 225), smoking up to 36 years (n = 251) and physical health status at 36 years (n-61)
  2. ** Index of definition: 1 = no symptoms; 2 = 1-4 symptoms; 3-7 = 5 or more symptoms