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Table 1 Baseline and pre-index characteristics of propensity score-matched study sample

From: One-year risk of psychiatric hospitalization and associated treatment costs in bipolar disorder treated with atypical antipsychotics: a retrospective claims database analysis

Variable Aripiprazole (n = 461) Ziprasidone (n = 461) p-value Aripiprazole (n = 737) Olanzapine (n = 737) p-value Aripiprazole (n = 770) Quetiapine (n = 770) p-value Aripiprazole (n = 771) Risperidone (n = 771) p-value
Age, mean (SD) 37.4 (11.6) 37.9 (11.1) 0.514 37.5 (12.0) 37.7 (11.9) 0.758 37.1 (11.9) 36.5 (11.4) 0.315 37.1 (11.9) 37.1 (11.2) 0.998
Sex, n (% men) 337 (73.1) 333 (722) 0.995 483 (65.5) 467 (63.4) 0.384 515 (66.9) 541 (70.3) 0.154 515 (66.8) 511 (66.3) 0.829
Psychiatric hospitalization, n (%) 159 (34.5) 160 (34.7) 0.945 179 (24.3) 182 (24.7) 0.856 178 (23.1) 178 (23.1) 1.000 180 (23.3) 180 (23.3) 1.000
Diabetes, n (%) 36 (7.8) 33 (7.2) 0.707 40 (5.4) 47 (6.4) 0.439 45 (5.8) 38 (4.9) 0.430 45 (5.8) 44 (5.7) 0.913
Hyperlipidemia, n (%) 75 (16.3) 81 (17.6) 0.598 123 (16.7) 131 (17.8) 0.581 130 (16.9) 130 (16.9) 1.000 130 (16.9) 119 (15.4) 0.446
Mood stabilizer exposure, n (%):             
   Carbamazapine 13 (2.8) 15 (3.3) 0.701 25 (3.4) 27 (3.7) 0.778 28 (3.6) 29 (3.8) 0.893 27 (3.5) 29 (3.8) 0.893
   Lamotrigine 72 (15.6) 75 (16.3) 0.787 116 (15.7) 115 (15.6) 0.943 137 (17.8) 134 (17.4) 0.841 136 (17.6) 134 (17.4) 0.841
   Lithium 67 (14.5) 70 (15.2) 0.781 106 (14.4) 104 (14.1) 0.882 115 (14.9) 108 (14.0) 0.612 115 (14.9) 108 (14.0) 0.612
   Oxcarbazepine 34 (7.4) 38 (8.2) 0.623 60 (8.1) 65 (8.8) 0.640 75 (9.7) 68 (8.8) 0.539 75 (9.7) 68 (8.8) 0.539
   Topiramate 43 (9.3) 46 (10.0) 0.738 68 (9.2) 65 (8.8) 0.785 81 (10.5) 85 (11.0) 0.742 80 (10.4) 85 (11.0) 0.742
   Valproate 83 (18.0) 84 (18.2) 0.932 159 (21.6) 156 (21.2) 0.849 165 (21.4) 168 (21.8) 0.853 165 (21.4) 168 (21.8) 0.853
Charlson comorbidity index, mean (SD) 0.3 (0.7) 0.4 (0.9) 0.388 0.3 (0.7) 0.3 (0.8) 0.432 0.2 (0.6) 0.2 (0.7) 0.746 0.3 (0.8) 0.3 (0.8) 0.468
  1. P-values were calculated based on t-tests for continuous variables and chi square tests for categorical variables.