Variable | Aripiprazole (n = 461) | Ziprasidone (n = 461) | p-value | Aripiprazole (n = 737) | Olanzapine (n = 737) | p-value | Aripiprazole (n = 770) | Quetiapine (n = 770) | p-value | Aripiprazole (n = 771) | Risperidone (n = 771) | p-value |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Age, mean (SD) | 37.4 (11.6) | 37.9 (11.1) | 0.514 | 37.5 (12.0) | 37.7 (11.9) | 0.758 | 37.1 (11.9) | 36.5 (11.4) | 0.315 | 37.1 (11.9) | 37.1 (11.2) | 0.998 |
Sex, n (% men) | 337 (73.1) | 333 (722) | 0.995 | 483 (65.5) | 467 (63.4) | 0.384 | 515 (66.9) | 541 (70.3) | 0.154 | 515 (66.8) | 511 (66.3) | 0.829 |
Psychiatric hospitalization, n (%) | 159 (34.5) | 160 (34.7) | 0.945 | 179 (24.3) | 182 (24.7) | 0.856 | 178 (23.1) | 178 (23.1) | 1.000 | 180 (23.3) | 180 (23.3) | 1.000 |
Diabetes, n (%) | 36 (7.8) | 33 (7.2) | 0.707 | 40 (5.4) | 47 (6.4) | 0.439 | 45 (5.8) | 38 (4.9) | 0.430 | 45 (5.8) | 44 (5.7) | 0.913 |
Hyperlipidemia, n (%) | 75 (16.3) | 81 (17.6) | 0.598 | 123 (16.7) | 131 (17.8) | 0.581 | 130 (16.9) | 130 (16.9) | 1.000 | 130 (16.9) | 119 (15.4) | 0.446 |
Mood stabilizer exposure, n (%): | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   Carbamazapine | 13 (2.8) | 15 (3.3) | 0.701 | 25 (3.4) | 27 (3.7) | 0.778 | 28 (3.6) | 29 (3.8) | 0.893 | 27 (3.5) | 29 (3.8) | 0.893 |
   Lamotrigine | 72 (15.6) | 75 (16.3) | 0.787 | 116 (15.7) | 115 (15.6) | 0.943 | 137 (17.8) | 134 (17.4) | 0.841 | 136 (17.6) | 134 (17.4) | 0.841 |
   Lithium | 67 (14.5) | 70 (15.2) | 0.781 | 106 (14.4) | 104 (14.1) | 0.882 | 115 (14.9) | 108 (14.0) | 0.612 | 115 (14.9) | 108 (14.0) | 0.612 |
   Oxcarbazepine | 34 (7.4) | 38 (8.2) | 0.623 | 60 (8.1) | 65 (8.8) | 0.640 | 75 (9.7) | 68 (8.8) | 0.539 | 75 (9.7) | 68 (8.8) | 0.539 |
   Topiramate | 43 (9.3) | 46 (10.0) | 0.738 | 68 (9.2) | 65 (8.8) | 0.785 | 81 (10.5) | 85 (11.0) | 0.742 | 80 (10.4) | 85 (11.0) | 0.742 |
   Valproate | 83 (18.0) | 84 (18.2) | 0.932 | 159 (21.6) | 156 (21.2) | 0.849 | 165 (21.4) | 168 (21.8) | 0.853 | 165 (21.4) | 168 (21.8) | 0.853 |
Charlson comorbidity index, mean (SD) | 0.3 (0.7) | 0.4 (0.9) | 0.388 | 0.3 (0.7) | 0.3 (0.8) | 0.432 | 0.2 (0.6) | 0.2 (0.7) | 0.746 | 0.3 (0.8) | 0.3 (0.8) | 0.468 |