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Table 5 Overactive regions during self-evaluation (vs. other-evaluation) in patients (vs. controls): group x level interaction (Figures 4 and 5 )

From: Self-evaluation in schizophrenia: an fMRI study with implications for the understanding of insight

Cerebral region

Peak talairach coordinates x, y, z(range)

3-D Cluster size (in voxels)

Significance level

POSITIVE TRAITS

   

Right Anterior Cingulate, BA32

8, 45, -6

57

p = 0.0017

Right Precuneus, BA7

18, -70, 42

17

p = 0.0056

Left Precuneus, BA7

-14, -59, 48

21

p = 0.007#

NEGATIVE TRAITS

   

No interaction found

   

MENTAL ILLNESS TRAITS

   

Left Superior Frontal Gyrus, BA8*

-6, 31, 47(5, 21, 47 inc. R med frontal gyrus)

30

p = 0.0033

Right Middle Frontal Gyrus, BA10

38, 50, 0

19

p = 0.007#

PHYSICAL ILLNESS TRAITS

   

Left Anterior Cingulate, BA32

-15, 42, -6

70

p = 0.0006

Right Inferior Parietal Lobule, BA40

50, -30, 25

28

p = 0.0021

Left Inferior Parietal Lobule, BA40 / Left Postcentral Gyrus, BA2

-41, -26, 30

31

p = 0.0024

  1. *Became significant after analysis with response time as a co-variate.
  2. #Cluster level significance level, p<.005. BA: Brodmann Area.