Skip to main content

Table 5 PANSS total score, QLS functional domain scores, and remission at baseline and changes at 6 Months and at 12 months

From: Schizophrenia symptoms and functioning in patients receiving long-term treatment with olanzapine long-acting injection formulation: a pooled analysis

 

Categories

 

Scores

 

A – (N)=162

B – (N)=434

C – (N)=208

D – (N)=303

E – (N)=72

Overall – (N) = 1182

PANSS Total

  Baseline

 

45.56 (9.22)

55.29 (11.19)

64.91 (12.80)

71.50 (10.74)

93.63 (14.64)

61.53 (16.12)

  6 months

 

−4.39 (8.95)

−6.41 (11.09)

−10.80(12.98)

−9.73 (12.56)

−24.90(21.70)

−8.77 (13.14)

  12 months

 

−3.79 (11.55)

−6.32 (12.14)

−12.94(12.78)

−12.63(13.11)

−30.39(20.72)

−9.75 (14.29)

QLS Interpersonal

  Baseline

 

3.75 (1.03)

2.48 (1.00)

3.56 (1.02)

2.22 (1.03)

2.00 (0.98)

2.77 (1.19)

  6 months

 

0.02 (0.85)

0.38 (0.91)

0.11 (0.87)

0.41 (0.80)

0.42 (0.85)

0.28 (0.88)

  12 months

 

0.20 (0.89)

0.47 (0.99)

0.03 (0.92)

0.46 (0.82)

0.61 (0.83)

0.34 (0.93)

QLS Instrumental

  Baseline

 

4.26 (0.73)

1.75 (0.97)

4.11 (0.64)

1.50 (0.94)

1.27 (0.99)

2.53 (1.49)

  6 months

 

−0.34 (1.13)

0.52 (1.16)

−0.10 (0.97)

0.51 (1.13)

0.43 (1.07)

0.26 (1.16)

  12 months

 

−0.19 (1.04)

0.70 (1.27)

−0.10 (1.02)

0.68 (1.25)

1.05 (1.19)

−0.41 (1.25)

Remission – based on observed cases

n (%)

 

A

B

C

D

E

Overall

Baseline - cross-sectional

 

137 (84.6)

266 (61.3)

119 (57.2)

87 (28.7)

1 (1.4)

610 (51.6)

  6 months - cross-sectional

 

114 (95.8)

235 (80.2)

125 (81.2)

104 (59.1)

15 (33.3)

594 (75.5)

  6 months - sustained

 

99 (83.2)

159 (54.3)

90 (58.4)

46 (26.1)

1 (2.2)

395 (50.2)

  12 months - cross-sectional

 

106 (93.8)

204 (81.9)

101 (82.8)

95 (67.9)

15 (42.9)

521 (79.1)

  12 months - sustained

 

104 (92.0)

191 (76.7)

95 (77.9)

76 (54.3)

10 (28.6)

476 (72.2)

  1. PANSS: Positive and Negative Symptoms Score, QLS: Heinrich Carpenter’s Quality of Life Scale, SD: standard deviation.