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Table 5 PANSS total score, QLS functional domain scores, and remission at baseline and changes at 6 Months and at 12 months

From: Schizophrenia symptoms and functioning in patients receiving long-term treatment with olanzapine long-acting injection formulation: a pooled analysis

  Categories  
Scores   A – (N)=162 B – (N)=434 C – (N)=208 D – (N)=303 E – (N)=72 Overall – (N) = 1182
PANSS Total
  Baseline   45.56 (9.22) 55.29 (11.19) 64.91 (12.80) 71.50 (10.74) 93.63 (14.64) 61.53 (16.12)
  6 months   −4.39 (8.95) −6.41 (11.09) −10.80(12.98) −9.73 (12.56) −24.90(21.70) −8.77 (13.14)
  12 months   −3.79 (11.55) −6.32 (12.14) −12.94(12.78) −12.63(13.11) −30.39(20.72) −9.75 (14.29)
QLS Interpersonal
  Baseline   3.75 (1.03) 2.48 (1.00) 3.56 (1.02) 2.22 (1.03) 2.00 (0.98) 2.77 (1.19)
  6 months   0.02 (0.85) 0.38 (0.91) 0.11 (0.87) 0.41 (0.80) 0.42 (0.85) 0.28 (0.88)
  12 months   0.20 (0.89) 0.47 (0.99) 0.03 (0.92) 0.46 (0.82) 0.61 (0.83) 0.34 (0.93)
QLS Instrumental
  Baseline   4.26 (0.73) 1.75 (0.97) 4.11 (0.64) 1.50 (0.94) 1.27 (0.99) 2.53 (1.49)
  6 months   −0.34 (1.13) 0.52 (1.16) −0.10 (0.97) 0.51 (1.13) 0.43 (1.07) 0.26 (1.16)
  12 months   −0.19 (1.04) 0.70 (1.27) −0.10 (1.02) 0.68 (1.25) 1.05 (1.19) −0.41 (1.25)
Remission – based on observed cases
n (%)   A B C D E Overall
Baseline - cross-sectional   137 (84.6) 266 (61.3) 119 (57.2) 87 (28.7) 1 (1.4) 610 (51.6)
  6 months - cross-sectional   114 (95.8) 235 (80.2) 125 (81.2) 104 (59.1) 15 (33.3) 594 (75.5)
  6 months - sustained   99 (83.2) 159 (54.3) 90 (58.4) 46 (26.1) 1 (2.2) 395 (50.2)
  12 months - cross-sectional   106 (93.8) 204 (81.9) 101 (82.8) 95 (67.9) 15 (42.9) 521 (79.1)
  12 months - sustained   104 (92.0) 191 (76.7) 95 (77.9) 76 (54.3) 10 (28.6) 476 (72.2)
  1. PANSS: Positive and Negative Symptoms Score, QLS: Heinrich Carpenter’s Quality of Life Scale, SD: standard deviation.