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Table 2 Use of healthcare services during pre- and post-index periods among all GAD patients newly started on benzodiazepines, by age*

From: Change in healthcare utilization and costs following initiation of benzodiazepine therapy for long-term treatment of generalized anxiety disorder: a retrospective cohort study

Healthcare Service

Patient Age

All Patients (N=866)

<50 Years (N=568)

≥50 Years (N=298)

Pre-Index

Post-Index

P-Value

Pre-Index

Post-Index

P-Value

Pre-Index

Post-Index

P-Value

Outpatient care

         

  Outpatient office visits

         

  Number (%) with ≥1 visits

         

   Accident-related

102 (18.0)

106 (18.7)

0.72

51 (17.1)

53 (17.8)

0.80

153 (17.7)

159 (18.4)

0.66

   Other possibly related

60 (10.6)

69 (12.1)

0.33

37 (12.4)

32 (10.7)

0.47

97 (11.2)

101 (11.7)

0.73

   All of above

142 (25.0)

152 (26.8)

0.45

79 (26.5)

73 (24.5)

0.51

221 (25.5)

225 (26.0)

0.80

   All other

379 (66.7)

410 (72.2)

0.03

209 (70.1)

223 (74.8)

0.14

588 (67.9)

633 (73.1)

<0.01

   All

521 (91.7)

562 (98.9)

<0.01

288 (96.6)

296 (99.3)

0.02

809 (93.4)

858 (99.1)

<0.01

  Mean (SD) number of visits

         

   Accident-related

4.2 (14.3)

5.3 (15.0)

0.15

5.9 (19.9)

6.4 (19.2)

0.69

4.8 (16.4)

5.7 (16.5)

0.18

   Other possibly related

2.5 (11.2)

3.6 (12.8)

0.06

3.0 (12.1)

5.7 (23.9)

0.05

2.7 (11.5)

4.3 (17.4)

<0.01

   All of above

5.5 (15.3)

7.2 (16.6)

0.02

7.4 (20.5)

9.6 (25.7)

0.11

6.1 (17.3)

8.0 (20.2)

<0.01

   All other

8.0 (13.7)

11.6 (15.9)

<0.01

12.8 (24.3)

17.7 (24.7)

<0.01

9.6 (18.2)

13.7 (19.6)

<0.01

   All

13.4 (18.2)

18.8 (19.1)

<0.01

20.2 (28.7)

27.3 (30.5)

<0.01

15.8 (22.6)

21.7 (23.9)

<0.01

 ED visits

         

  Number (%) with ≥1 visits

         

   Accident-related

44 (7.7)

48 (8.5)

0.60

15 (5.0)

15 (5.0)

>0.99

59 (6.8)

63 (7.3)

0.67

   Other possibly related

36 (6.3)

23 (4.0)

0.06

9 (3.0)

14 (4.7)

0.28

45 (5.2)

37 (4.3)

0.33

   All of above

67 (11.8)

61 (10.7)

0.51

21 (7.0)

24 (8.1)

0.62

88 (10.2)

85 (9.8)

0.79

   All other

51 (9.0)

58 (10.2)

0.44

18 (6.0)

24 (8.1)

0.29

69 (8.0)

82 (9.5)

0.23

   All

118 (20.8)

119 (21.0)

0.93

39 (13.1)

48 (16.1)

0.26

157 (18.1)

167 (19.3)

0.48

  Mean (SD) number of visits

         

   Accident-related

0.7 (3.7)

1.0 (6.1)

0.27

0.6 (3.4)

1.3 (15.5)

0.47

0.7 (3.6)

1.1 (10.3)

0.25

   Other possibly related

0.8 (4.8)

0.7 (5.5)

0.47

1.1 (15.1)

1.4 (15.6)

0.24

0.9 (9.6)

0.9 (10.2)

0.92

   All of above

1.2 (5.2)

1.3 (6.5)

0.88

1.6 (15.4)

1.6 (15.7)

0.81

1.4 (9.9)

1.4 (10.6)

0.98

   All other

0.8 (4.0)

1.0 (4.7)

0.43

0.6 (3.1)

0.8 (4.0)

0.51

0.7 (3.7)

0.9 (4.5)

0.30

   All

2.1 (6.4)

2.3 (7.9)

0.49

2.2 (15.6)

2.3 (16.1)

0.72

2.1 (10.5)

2.3 (11.4)

0.44

Hospitalizations

         

 Number (%) with ≥1 hospitalizations

         

  Accident-related

11 (1.9)

13 (2.3)

0.67

8 (2.7)

7 (2.3)

0.76

19 (2.2)

20 (2.3)

0.86

  Other possibly related

12 (2.1)

13 (2.3)

0.83

8 (2.7)

10 (3.4)

0.56

20 (2.3)

23 (2.7)

0.60

  All of above

18 (3.2)

22 (3.9)

0.50

12 (4.0)

11 (3.7)

0.78

30 (3.5)

33 (3.8)

0.67

  All other

23 (4.0)

17 (3.0)

0.29

14 (4.7)

11 (3.7)

0.44

37 (4.3)

28 (3.2)

0.19

  All

41 (7.2)

39 (6.9)

0.80

26 (8.7)

22 (7.4)

0.41

67 (7.7)

61 (7.0)

0.51

 Mean (SD) number of hospitalizations

         

  Accident-related

0.7 (6.1)

1.2 (11.2)

0.38

1.1 (8.6)

1.3 (10.1)

0.75

0.9 (7.0)

1.2 (10.8)

0.36

  Other possibly related

0.9 (7.3)

1.3 (12.1)

0.52

1.5 (10.9)

1.7 (11.0)

0.74

1.1 (8.7)

1.4 (11.7)

0.48

  All of above

1.2 (8.1)

1.7 (13.0)

0.40

1.7 (11.1)

1.8 (11.0)

0.98

1.4 (9.3)

1.7 (12.4)

0.47

  All other

0.9 (5.9)

0.5 (4.1)

0.13

1.7 (9.0)

0.8 (5.9)

0.11

1.2 (7.1)

0.6 (4.8)

0.03

  All

2.2 (9.9)

2.2 (13.6)

0.94

3.5 (14.1)

2.6 (12.4)

0.30

2.6 (11.6)

2.3 (13.2)

0.56

  1. GAD: Generalized anxiety disorder; SD: Standard deviation; ED: Emergency department.