The association between parental history of diagnosed mood/anxiety disorders and psychiatric symptoms and disorders in young adult offspring

Table 4 Adjusted odds ratios (OR) and 95% confidence intervals (CI) for the association between diagnosed parental mood and/or anxiety disorders and mental health outcomes among offspring, NDIT 2007-10

	n	Offspring diagnosis		Anxiety symptoms in offspring
		Mood disorder OR_adj (95% CI)	Anxiety disorder OR_adj (95% CI)	Social phobia OR_adj (95% CI)	Generalized anxiety disorder (GAD) OR_adj (95% CI)	Panic disorder OR_adj (95% CI)
Mother diagnosed with mood and/or anxiety disorder	564*	2.2 (1.1,4.5)	4.0 (2.1,7.8)	2.2 (1.2,4.0)	1.8 (0.7,4.1)	1.7 (0.8,3.5)
p-value		0.0263	<0.0001	0.0131	0.1966	0.1497
Offspring sex		2.4 (1.1,5.3)	2.4 (1.2,5.0)	1.4 (1.0,2.2)	3.6 (1.9,7.4)	2.6 (1.6,4.5)
p-value		0.0249	0.0183	0.0752	0.0002	0.0003
Mother university-educated (yes, no)		0.5 (0.2,1.0)	0.50 (0.2,1.00)	1.3 (0.9,2.0)	2.0 (1.1,3.6)	0.7 (0.4,1.2)
p-value		0.0542	0.0583	0.1614	0.0233	0.2050
Father diagnosed with mood and/or disorder**	454*	0.9 (0.2,2.8)	**	0.5 (0.2,1.1)	0.8 (0.2,2.2)	**
p-value		0.8862		0.1263	0.7112
Offspring sex		3.6 (1.4,11.1)		1.7 (1.1,2.7)	5.9 (2.6,15.9)
p-value		0.0115		0.0236	0.0001
Mother university-educated (yes, no)		0.4 (0.2,0.9)		1.1 (0.7,1.8)	1.9 (1.0,3.8)
p-value		0.0429		0.6206	0.0622

ISSN: 1471-244X