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Table 6 Mean antipsychotic dose prescribed

From: Antipsychotic dose escalation as a trigger for Neuroleptic Malignant Syndrome (NMS): literature review and case series report

 

NMS patients (n = 13)

Cases 1–5 “rapid dose escalators” (n = 5)

Cases 6–13 “non rapid dose escalators” (n = 8)

Clozapine titration

Mean cumulative total antipsychotic dose (mg) Days 1-15

3625.1

512.4

6102.5

893.8

Mean daily antipsychotic dose (mg) Days 1-15

241.7

34.2

406.8

63.8

Mean cumulative total antipsychotic dose (mg) Days 16-30

5202.8

4219.9

5817.2

2600

Mean daily antipsychotic dose (mg) Days 16-30

346.9

281.3

387.8

185.7

Mean Ratio (Days 16–30: Days 1–15)

1.4

7.3

1.1

2.9