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Table 2 Patient characteristics before switching from risperidone to olanzapine and from olanzapine to risperidone

From: Clinical consequences of switching from olanzapine to risperidone and vice versa in outpatients with schizophrenia: 36-month results from the worldwide schizophrenia outpatients health outcomes (W-SOHO) study

 

OLZ-RIS (n=162)

RIS-OLZ (n=136)

Age (years) a

37.2 ± 13.3

36.5 ± 12.5

Male (%)b

51.2

51.9

Age at first service contact for schizophrenia (years)a

27.6 ± 10.3

27.9 ± 10.5

Duration of illness (years)a

9.7 ± 10.1

8.8 ± 8.9

CGI-SCH overalla

3.5 ± 1.2

3.6 ± 1.2

CGI-SCH positivea

3.0 ± 1.4

3.0 ± 1.4

CGI-SCH negativea

3.1 ± 1.3

3.2 ± 1.3

CGI-SCH cognitivea

2.8 ± 1.3

3.1 ± 1.3

CGI-SCH depressivea

2.7 ± 1.3

3.0 ± 1.4

Current alcohol abuse (%)b,*

5.0

1.5

Current substance abuse (%)b

2.5

3.7

Being hostile (%)b

9.9

11.0

Having a spouse/partner (%)b

30.4

24.2

Living independently (%)b

55.9

49.6

Being socially active (%)b

80.1

77.8

Being employed (%)b

29.8

25.2

  1. a Data presented as mean (SD), t-test employed.
  2. b Data presented as %, chi-test employed.
  3. * Significant at p<0.05.
  4. OLZ-RIS: Patients who switched from olanzapine to risperidone.
  5. RIS-OLZ: Patients who switched from risperidone to olanzapine.
  6. CGI-SCH: Clinical Global Impression-Schizophrenia.