Altered monocyte activation markers in Tourette’s syndrome: a case–control study

BMC Psychiatry

Table 3 Analysis of TNF-alpha, sCD14, IL1-ra, and neopterin in co-morbid OCD subgroups

		TNF-alpha	sCD14	IL1-ra	Neopterin
		(pg/ml)	(ng/ml)	(ng/ml)	(nmol/l)
TS without OCD	mean ± SD	0.52 ± 0.17	6.9 ± 1.3	0.013 ± 0.014	5.10 ± 1.28
vs.	rank sum	18.82	21.05	22.25	16.50
TS with OCD	mean ± SD	0.40 ± 0.18	6.3 ± 1.4	0.034 ± 0.095	6.36 ± 2.15
	rank sum	26.28	26.38	22.59	24.13
	p-value* (n)	n.s. (9/31)	n.s. (12/32)	n.s. (12/32)	n.s. (12/31)
Control vs.	mean ± SD	0.55 ± 0.24	8.4 ± 2,0	0.041 ± 0.057	5.16 ± 1.75
TS with OCD	rank sum	40.49	47.67	42.73	31.69
	mean ± SD	0.40 ± 0.18	6.3 ± 1.4	0.034 ± 0.095	6.36 ± 2.15
	rank sum	27.35	23.33	30.64	44.19
	p-value* (n)	0.006 (37/31)	0.000 (41/32)	0.016 (42/32)	0.013 (42/31)
Control vs.	mean ± SD	0.55 ± 0.24	8.4 ± 2.0	0.041 ± 0.057	5.16 ± 1.75
TS without OCD	rank sum	23.91	30.01	30.01	27.17
	mean ± SD	0.52 ± 0.17	6.9 ± 1.3	0.013 ± 0.014	5.10 ± 1.28
	rank sum	21.83	16.71	18.71	28.67
	p-value* (n)	n.s. (37/9)	0.009 (41/12)	0.028 (42/12)	n.s. (42/12)

TS = Tourette’s syndrome, OCD = obsessive compulsive disorder, n = number, SD = standard deviation, n.s. = not significant, *Mann–Whitney U Test.

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