Skip to main content

Advertisement

Table 3 Analysis of TNF-alpha, sCD14, IL1-ra, and neopterin in co-morbid OCD subgroups

From: Altered monocyte activation markers in Tourette’s syndrome: a case–control study

   TNF-alpha sCD14 IL1-ra Neopterin
   (pg/ml) (ng/ml) (ng/ml) (nmol/l)
TS without OCD mean ± SD 0.52 ± 0.17 6.9 ± 1.3 0.013 ± 0.014 5.10 ± 1.28
vs. rank sum 18.82 21.05 22.25 16.50
TS with OCD mean ± SD 0.40 ± 0.18 6.3 ± 1.4 0.034 ± 0.095 6.36 ± 2.15
  rank sum 26.28 26.38 22.59 24.13
  p-value* (n) n.s. (9/31) n.s. (12/32) n.s. (12/32) n.s. (12/31)
Control vs. mean ± SD 0.55 ± 0.24 8.4 ± 2,0 0.041 ± 0.057 5.16 ± 1.75
TS with OCD rank sum 40.49 47.67 42.73 31.69
  mean ± SD 0.40 ± 0.18 6.3 ± 1.4 0.034 ± 0.095 6.36 ± 2.15
  rank sum 27.35 23.33 30.64 44.19
  p-value* (n) 0.006 (37/31) 0.000 (41/32) 0.016 (42/32) 0.013 (42/31)
Control vs. mean ± SD 0.55 ± 0.24 8.4 ± 2.0 0.041 ± 0.057 5.16 ± 1.75
TS without OCD rank sum 23.91 30.01 30.01 27.17
  mean ± SD 0.52 ± 0.17 6.9 ± 1.3 0.013 ± 0.014 5.10 ± 1.28
  rank sum 21.83 16.71 18.71 28.67
  p-value* (n) n.s. (37/9) 0.009 (41/12) 0.028 (42/12) n.s. (42/12)
  1. TS = Tourette’s syndrome, OCD = obsessive compulsive disorder, n = number, SD = standard deviation, n.s. = not significant, *Mann–Whitney U Test.