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Table 1 Patient Characteristics by 25-OH Vitamin D Levels

From: Vitamin D deficiency and psychotic features in mentally ill adolescents: A cross-sectional study

 

All N = 104

Deficient (<20 ng/ ml) N = 35

Not Deficient N = 69

p-value*

Variable

X (1SD) or n (%)

X (1SD) or n (%)

X (1SD) or n (%)

 

Demographics

    

Age

15.38 ± 1.6

15.28 ±  1.63

15.43 ±  1.60

0.66

Sex (M/F) (%Male)

29/75 (27.9)

11/24 (31.4)

18/51 (27.9)

0.57

Race (White/Black/Hispanic/ Asian/Biracial) (%White)

76/15/1/5/7 (73.1)

17/9/0/5/4 (50.0)

59/6/1/0/3 (67.0)

0.0003

Residence (Urban/ Suburban or Rural) (%Urban)

10/94 (9.6)

3/32 (8.6)

7/62 (6.7)

0.80

Insurance (Private/ Medicaid) (%Private)

65/39 (62.5)

19/16 (54.3)

46/23 (66.7)

0.22

Smoking Status (Yes/No) (%Yes)

18/67 (21.2)

9/20 (31)

9/47 (16.1)

0.11

Inpatient or Outpatient Status (Inpatient/ Outpatient) (% Inpatient)

34/70 (32.7)

14/21 (40)

20/49 (29.0)

0.26

Metabolic Variables

    

Body Mass Index (BMI)

25.2 ± 7.6

26.1 ± 8.4

24.7 ± 7.2

0.39

Glucose

93.9 ± 18.1

91.7 ± 13.8

94.9 ± 19.7

0.42

Cholesterol, total

167.4 ± 34.4

167.6 ± 30.8

167.3 + 36.7

0.98

High Density Lipoprotein (HDL)

53.1 ± 13.9

54.3 ± 13.5

52.4 ± 14.3

0.63

Low Density Lipoprotein (LDL)

94.0 ± 25.0

95.7 ± 21.9

93.0 ± 26.8

0.71

Triglycerides

96.0 ± 69.3

87.6 ± 57.6

100.5 ± 75.2

0.52

Pulse

79.6 ± 15.6

78.4 ± 12.4

80.3 ± 16.7

0.57

Diastolic Blood Pressure

67.6 ± 9.0

69.1 ± 9.3

66.7 ± 8.7

0.20

Systolic Blood Pressure

115.3 ± 12.7

116.9 ± 14.3

114.5 ± 11.9

0.39

Illness Features and Family History

    

Psychosis N, (%)

25 (24.0)

14 (40.0)

11 (15.9)

0.007

Immediate Family Psychosis N, (%)

10 (9.6)

4 (11.4)

6 (8.7)

0.66

Extended Family Psychosis N, (%)

10 (9.6)

5 (14.3)

5 (7.3)

0.25

Illness Age of Onset (Prepubertal/ Adolescent) (% Prepubertal)

45/55 (45)

14 (41.2)

31 (47.0)

0.69

DSM-IV diagnoses, N (%)

    

Bipolar Disorders

37 (36)

13 (37)

24 (34.8)

0.81

Unipolar Depressive

36 (35)

9 (25.7)

27 (39.1)

0.17

Mood Disorder NOS

15 (14)

6 (17.1)

9 (13.0)

0.57

Anxiety Disorder NOS

5 (5)

2 (5.7)

3 (4.3)

0.76

Psychotic Disorder NOS

8 (7.7)

5 (14.3)

3 (4.3)

0.07

Other (Yes/No) (%Yes)

3 (1.3)

0 (0.0)

3 (4.3)

0.21

Current Medication Exposure, N (%)

    

Stimulants N, (%)

6 (5.8)

2(5.7)

4 (5.8)

0.99

Antidepressants N, (%)

44 (42.3)

11 (31.4)

33 (47.8)

0.11

Antipsychotics N, (%)

35 (33.7)

12 (34.3)

23 (66.7)

0.92

Anticonvulsants N, (%)

18 (17.3)

5 (14.9))

13 (18.8)

0.56

Benzodiazepines N, (%)

6 (5.8)

3 (8.6)

3 (4.35)

0.38

Other medications

31 (29.8)

8 (22.9)

23 (33.3)

0.27

Past Medication Exposure, N (%)

    

Stimulants N, (%)

18 (17.3)

7 (20.0)

11 (15.9)

0.60

Antidepressants N, (%)

42 (40.4)

12 (34.3)

30 (56.5)

0.37

Antipsychotics N, (%)

21 (20.2)

6 (17.1)

15 (21.7)

0.58

Anticonvulsants N, (%)

20 (19.2)

4 (11.4)

16 (23.2)

0.15

Benzodiazepines N, (%)

3 (2.88)

0 (0.0)

3 (4.35)

0.21

Other medications

9 (8.7)

2 (5.7)

7 (10.1)

0.4

  1. *Evaluated by ANOVA, Wilcoxon rank sum test, χ², or Fisher’s exact test.
  2. Missing data were present for the following (N): BMI, 4;, glucose 5; cholesterol and HDL 50; LDL 49;
  3. TG 49, pulse 4, DBP and SBP 5; calcium 6; height 4; waist circumference 50; weight 3.