Table 3 Linear correlations of demographics and clinical variables to patient anterior insula GMV
Demographic/clinical variable | Left anterior insula | Right anterior insula |
|---|---|---|
Predicted IQ | r(117) = .03 | r(117) = −.01 |
Age of onset of illness | r(124) = −.02 | r(124) = −.04 |
Years of Education | r(125) = −.10 | r(125) = −.05 |
Antidepressant dose (mg/day) | r(110) = .09 | r(110) = .02 |
Antipsychotic dose (mg/day) | r(110) = −.04 | r(110) = −.10 |
Mood stabiliser dose (mg/day) | r(110) = .03 | r(110) = .04 |
Social and occupational functioning (SOFAS) | r(119) = −.12 | r(119) = −.11 |
Psychological distress (K-10) | r(125) = .08 | r(125) = .06 |
Depression (HDRS) | r(121) = .10 | r(121) = −.04 |
Depression (DASS Depression subscore) | r(116) = .11 | r(116) = .00 |
Anxiety (DASS Anxiety subscore) | r(116) = −.01 | r(116) = −.03 |
Stress (DASS Stress subscore) | r(116) = .08 | r(116) = .03 |
Social interaction anxiety (SIAS) | r(122) = .18* | r(122) = .23** |
Symptom severity (BPRS Total) | r(116) = .12 | r(116) = .03 |
Positive symptoms (BPRS Positive Symptoms subscore) | r(116) = .10 | r(116) = .10 |
Negative symptoms (BPRS Negative Symptoms subscore) | r(116) = .12 | r(116) = .02 |
Depression (BPRS Depression subscore) | r(116) = .01 | r(116) = −.09 |
Mania (BPRS Mania subscore) | r(116) = .08 | r(116) = .06 |