Table 4 Quadratic correlations of demographics and clinical variables to patient anterior insula GMV
Demographic/clinical variable | Left anterior insula | Right anterior insula |
|---|---|---|
Predicted IQ | r(117) = .03 | r(117) = .04 |
Age of onset of illness | r(124) = .07 | r(124) = .09 |
Years of Education | r(125) = .16 | r(125) = .13 |
Antidepressant dose (mg/day) | r(64) = .13 | r(64) = .06 |
Antipsychotic dose (mg/day) | r(60) = .20 | r(60) = .26 |
Mood stabiliser dose (mg/day) | r(25) = .25 | r(25) = .17 |
Social and occupational functioning (SOFAS) | r(119) = .12 | r(119) = .13 |
Psychological distress (K-10) | r(125) = .12 | r(125) = .10 |
Depression (HDRS) | r(121) = .17 | r(121) = .19 |
Depression (DASS Depression subscore) | r(116) = .13 | r(116) = .02 |
Anxiety (DASS Anxiety subscore) | r(116) = .14 | r(116) = .13 |
Stress (DASS Stress subscore) | r(116) = .19 | r(116) = .09 |
Social interaction anxiety (SIAS) | r(122) = .20 | r(122) = .28** |
Symptom severity (BPRS Total) | r(117) = .17 | r(117) = .29** |
Positive symptoms (BPRS Positive Symptoms subscore) | r(117) = .17 | r(117) = .32** |
Negative symptoms (BPRS Negative Symptoms subscore) | r(117) = .10 | r(117) = .06 |
Depression (BPRS Depression subscore) | r(117) = .07 | r(117) = .10 |
Mania (BPRS Mania subscore) | r(116) = .16 | r(116) = .22 |