From: Neurocognitive profiles in treatment-resistant bipolar I and bipolar II disorder depression
Variable | Total sample | BD I | BD II | p | |
---|---|---|---|---|---|
n = 19 | n = 32 | ||||
Demographics | Gender (male), n (%) | 24 (47.1) | 7 (36.8) | 17 (53.1) | 0.201) |
Age (years) | 45.7 (10.5) | 49.2 (9.2) | 43.6 (10.8) | 0.062) | |
Education (years) | 13.8 (3.2) | 12.6 (3.2) | 14.5 (3.0) | 0.04 2) | |
Premorbid IQ | 112.9 (3.7) | 112.0 (3.9)a | 113.5 (3.4)b | 0.182) | |
Course of illness | Duration of illness (years) | 30.6 (11.4) | 33.4 (9.4)a | 29.1 (12.2) | 0.192) |
Hospitalizations due to depressive episodes | 4.3 (3.9) | 4.7 (4.8)c | 4.1 (3.5)d | 0.823) | |
History of psychotic symptoms, n (%) | 24 (48.0) | 16 (84.2) | 8 (25.8)e | <0.01 1) | |
Number of psychotic episodes | 1.8 (3.0) | 3.6 (3.6)c | 0.8 (2.1)f | <0.01 3) | |
Lifetime DSM-IV-TR diagnosis | Substance abuse, n (%) | 15 (29.4) | 6 (31.6) | 9 (28.1) | 1.001) |
Anxiety, n (%) | 14 (29.2) | 8 (47.1)g | 6 (19.4)e | 0.061) | |
Symptom rating scales | MADRS | 37.0 (6.6) | 36.8 (6.6) | 37.2 (6.6) | 0.872) |
PANSS pos | 9.8 (3.4) | 9.7 (3.6)c | 9.8 (3.4) | 0.763) | |
GAF-S | 37.3 (10.9) | 41.0 (9.8)a | 35.3 (11.1) | 0.103) |