Table 4 Correlations between demographic and illness characteristics and neurocognitive performance for the total sample of 51 inpatients with therapy-resistant BD depression
From: Neurocognitive profiles in treatment-resistant bipolar I and bipolar II disorder depression
Neurocognitive domain | Demographic characteristics | Course of illness | Current symptoms | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gender (male) | Age | Education | Premorbid IQ | BD I | Duration of illness | Number of hospitalizations due to depresssive episodes | History of psychotic symptoms | Number of psychotic episodes | Comorbid substance abuse | Comorbid anxiety | MADRS | PANSS pos | GAF-S | |
Test | (NART) | |||||||||||||
Speed of Processing | -0.09 | -0.21 | 0.25 | 0.20 | -0.25 | -0.12 | -0.02 | -0.14 | -0.10 | 0.09 | 0.02 | 0.05 | -0.01 | -0.05 |
BACS–Symbol Coding | -0.19 | -0.29* | 0.28 | 0.27 | -0.06 | -0.27 | -0.14 | -0.04 | 0.01 | 0.08 | 0.17 | -0.06 | -0.15 | 0.06 |
Fluency | -0.09 | -0.11 | 0.20 | 0.06 | -0.35* | 0.10 | 0.22 | -0.20 | -0.24 | 0.01 | 0.05 | -0.01 | -0.05 | 0.17 |
TMT-A | -0.02 | -0.19 | 0.23 | 0.14 | -0.22 | -0.15 | -0.11 | -0.09 | -0.11 | -0.01 | -0.09 | 0.11 | 0.09 | -0.22 |
Attention/Vigilance | -0.20 | -0.46** | 0.14 | 0.00 | -0.11 | -0.43** | -0.29 | -0.08 | -0.10 | 0.23 | 0.20 | -0.19 | -0.06 | -0.10 |
CPT | ||||||||||||||
Working memory | -0.17 | -0.43** | 0.36** | 0.16 | -0.13 | -0.27 | -0.01 | -0.07 | -0.07 | 0.04 | 0.19 | 0.01 | -0.20 | 0.05 |
Spatial Span | -0.10 | -0.42** | 0.27 | 0.13 | -0.12 | -0.21 | 0.09 | 0.07 | 0.08 | 0.12 | 0.32 | 0.10 | -0.20 | 0.00 |
Letter-Number Span | -0.17 | -0.38** | 0.37** | 0.16 | -0.11 | -0.31* | -0.10 | -0.20 | -0.20 | -0.05 | 0.05 | -0.05 | -0.15 | 0.06 |
Verbal learning | -0.04 | -0.37** | 0.32* | 0.36* | -0.14 | -0.25 | -0.05 | -0.20 | -0.14 | 0.05 | 0.01 | 0.00 | -0.25 | 0.02 |
HVLT-R | ||||||||||||||
Visual learning | -0.09 | -0.28 | 0.34 | 0.16 | -0.21 | -0.14 | 0.17 | -0.17 | -0.12 | 0.12 | 0.23 | -0.04 | -0.14 | 0.03 |
BVMT-R | ||||||||||||||
Reasoning | -0.21 | -0.19 | 0.22 | 0.04 | 0.04 | -0.06 | -0.13 | 0.10 | 0.08 | 0.18 | 0.21 | 0.07 | 0.02 | -0.04 |
Mazes | ||||||||||||||
Mean Composite score | -0.18 | -0.40** | 0.36** | 0.22 | -0.19 | -0.26 | -0.07 | -0.13 | -0.12 | 0.10 | 0.15 | -0.02 | -0.13 | -0.04 |
IQ-decline | -0.21 | 0.17 | -0.41** | -0.17 | 0.43** | -0.05 | 0.17 | 0.40** | 0.41* | -0.17 | -0.01 | 0.05 | 0.26 | -0.17 |
NART-WASI | ||||||||||||||