The relationship between obesity and neurocognitive function in Chinese patients with schizophrenia

BMC Psychiatry

Table 3 Comparisons of cognitive function measures across different BMI groups ^a

Characteristic	Underweight (n = 57)	Normal weight (n = 358)	Overweight (n = 319)	Obese (n = 162)	F	p value
WAIS-R Digit Symbol	47.5 ± 15.8	48.3 ± 14.1	46.6 ± 12.8	44.0 ± 13.2	3.922	0.009^b
Trail Making Test A	56.6 ± 23.7	52.5 ± 24.3	54.9 ± 29.5	55.6 ± 27.3	0.842	0.471
Trail Making Test B	112.3 ± 59.0	106.7 ± 54.6	114.4 ± 61.4	123.7 ± 55.5	2.784	0.040^c
WCST Perseverative Errors	40.4 ± 25.8	42.7 ± 24.7	42.9 ± 23.7	41.6 ± 26.5	0.241	0.868
WCST Categories Completed	2.7 ± 2.2	2.5 ± 2.1	2.6 ± 2.1	2.8 ± 2.2	0.491	0.688
WAIS-R Digit Span	12.0 ± 3.8	12.5 ± 3.5	12.3 ± 3.1	11.9 ± 3.0	1.606	0.186
WMS-R Visual Reproduction	8.9 ± 2.8	9.3 ± 3.0	8.6 ± 2.9	8.2 ± 3.5	5.921	0.001^d
Composite z score	0.10 ± 0.09	0.20 ± 0.03	0.10 ± 0.03	0.01 ± 0.05	4.365	0.005^e

^a Asian BMI categories(kg/m²): underweight (< 18.5), normal weight(18.5-22.9), overweight (23–27.4) and obese (≥ 27.5); Data are presented as mean ± SD.
^bnormal weight vs obese, P = 0.001; ^cnormal weight vs obese, P = 0.004; ^dnormal weight vs obese, P = 0.001;normal weight vs overweight, P = 0.012 ^e normal weight vs obese, P = 0.004;
Abbreviation: WAIS, Wechsler Adult Intelligence Scale-Revised; WCST, Computerized Wisconsin Card Sorting Test; WMS-R, Wechsler Memory Scale-Revised; BMI, Body mass index.

ISSN: 1471-244X