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Table 3 Selected physical comorbidities in incident methylphenidate users and controls in 2005 to 2006

From: Comorbidities in ADHD children treated with methylphenidate: a database study

 

Male

Female

Diagnostic Group

Incident users

Controls

P-value

Incident users

Controls

P-value

(N=13,460)%1

(N=978,790)%1

(N=3,837)%1

(N=1,000,300)%1

Pre-existing cardiovascular disorders

2.00

1.24

<0.01

2.06

1.18

<0.01

  Angina pectoris

0.13

0.19

0.34

0.16

0.18

0.90

  Arterial occlusive disease

0.01

0.02

0.98

0.08

0.03

0.04

  Potentially life threatening arrhythmias

0.51

0.17

<0.01

0.57

0.14

<0.01

  Cardiomyopathy

0.10

0.05

0.02

0.03

0.05

0.57

  Severe congenital heart disease

1.23

0.78

<0.01

1.20

0.75

<0.01

  Heart failure

0.09

0.05

0.02

0.03

0.05

0.69

  Myocardial infarction

0.01

0.01

0.64

0.03

0.02

0.43

  Severe hypertension

0.07

0.05

0.34

0.05

0.05

0.82

Pre-existing cerebrovascular disorders

0.19

0.11

<0.01

0.13

0.10

0.36

Stroke

0.10

0.05

0.02

0.10

0.04

0.02

Glaucoma

0.39

0.33

0.34

0.34

0.35

0.96

Hyperthyroidism

1.22

0.15

<0.01

0.89

0.27

<0.01

  1. 1 Percentages could add up to more than 100% since insurees could have more than one type of comorbidity.