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Table 3 Selected physical comorbidities in incident methylphenidate users and controls in 2005 to 2006

From: Comorbidities in ADHD children treated with methylphenidate: a database study

  Male Female
Diagnostic Group Incident users Controls P-value Incident users Controls P-value
(N=13,460)%1 (N=978,790)%1 (N=3,837)%1 (N=1,000,300)%1
Pre-existing cardiovascular disorders 2.00 1.24 <0.01 2.06 1.18 <0.01
  Angina pectoris 0.13 0.19 0.34 0.16 0.18 0.90
  Arterial occlusive disease 0.01 0.02 0.98 0.08 0.03 0.04
  Potentially life threatening arrhythmias 0.51 0.17 <0.01 0.57 0.14 <0.01
  Cardiomyopathy 0.10 0.05 0.02 0.03 0.05 0.57
  Severe congenital heart disease 1.23 0.78 <0.01 1.20 0.75 <0.01
  Heart failure 0.09 0.05 0.02 0.03 0.05 0.69
  Myocardial infarction 0.01 0.01 0.64 0.03 0.02 0.43
  Severe hypertension 0.07 0.05 0.34 0.05 0.05 0.82
Pre-existing cerebrovascular disorders 0.19 0.11 <0.01 0.13 0.10 0.36
Stroke 0.10 0.05 0.02 0.10 0.04 0.02
Glaucoma 0.39 0.33 0.34 0.34 0.35 0.96
Hyperthyroidism 1.22 0.15 <0.01 0.89 0.27 <0.01
  1. 1 Percentages could add up to more than 100% since insurees could have more than one type of comorbidity.