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Table 1 Frequencies of medications and distributions of temperament traits and depressive symptoms during the study

From: TPH1A218C polymorphism and temperament in major depression

Variable

Baseline (n = 97)

Endpoint (6 weeks, n = 87)

Antidepressive medication

N

%

N

%

Citalopram

50

51.5

44

50.6

Paroxetine

12

12.4

11

12.6

Fluoxetine

35

36.1

32

36.8

Use of hypnotics

32

33.0

  

Use of anxiolytics

22

22.7

  

Temperament scores

mean

SD

mean*

SD

NS

19.5

7.5

20.8

7.4

HA

23.7

6.9

21.8

7.9

RD

15.5

3.9

15.9

3.7

P

4.3

2.0

4.3

2.0

MADRS score

26.9

5.6

12.2

8.2

Antidepressant dose, mg

19.8

2.7

22.3

6.5

  1. *n = 86.
  2. NS novelty seeking, HA harm avoidance, RD reward dependence, P persistence.