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Table 3 Binary logistic regression analyses for variables of genotype, adversity, gender, age, SES, FSIQ, and Genotype (G) × Environment (E)

From: No interaction between serotonin transporter gene (5-HTTLPR) polymorphism and adversity on depression among Japanese children and adolescents

Genotype (G)

B

SE

Wald

 p value

OR

95% CI

  0.11

   0.32

0.119

  0.730

    1.12

0.600-2.073

Adversity (E)

B

SE

Wald

 p value

OR

95% CI

 21.48

 12118.64

0.000

  0.000

 2129489594

0.000-

Gender

B

SE

Wald

 p value

OR

95% CI

 −1.06

     0.4

 7.11

  0.01

    0.35

0.158-0.754

Age

B

SE

Wald

 p value

OR

95% CI

  0.09

     0.1

 0.73

  0.39

    1.09

0.894-1.332

SES

B

SE

Wald

 p value

OR

95% CI

  −0.5

   0.31

 2.56

  0.110

    0.61

0.330-1.119

FSIQ

B

SE

Wald

 p value

OR

95% CI

 −0.07

   0.02

 10.9

    0

    0.93

00.892-0.971

Gene × Environment(E)

B

SE

Wald

 p value

OR

95% CI

 20.86

 13894.65

0.000

  0.000

 1142607181

0.000-

  1. note: B=unstandardized partial regression coefficient, SE = standard error, OR = odds ratio, Wald = (SE/B)2, CI = confidence interval.
  2. Dependent variable is existence of diagnosis (0 = no, 1 = childhood depression).
  3. Independent variables: 5-HTTLPR genotype (0 = s/s, 1 = s/l, 2 = l/l), Adversity (maternal depression: 0 = no, 1 = yes). Gender (0 = female, 1 = male), SES (from 0 = low income to 5 = high income).
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BMC Psychiatry

ISSN: 1471-244X

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