| Placebo | Olanzapine |
---|---|---|
 | (N = 52) | (N = 104) |
Female gender, n (%) | 27 (51.9) | 63 (60.6) |
Age in years, mean (SD) | 36.3 (9.5) | 40.0 (11.0) |
Age in years at onset of BD, mean (SD) | 29.1 (8.8) | 33.1 (10.9) |
Prior episodes, mean (SD) | Â | Â |
 Manic | 3.02 (3.07) | 3.32 (4.46) |
 Depressive | 3.77 (3.35) | 4.54 (5.69) |
 Mixed | 0.23 (0.70) | 0.13 (0.48) |
Weight in kg, mean (SD) | 64.02 (12.14) | 59.04 (12.35) |
Illness severity scores, mean (SD) | Â | Â |
 MADRS total | 28.62 (8.01) | 29.00 (6.15) |
 YMRS total | 0.85 (1.32) | 0.88 (1.32) |
 HAMD-17 total | 22.69 (4.08) | 23.10 (3.78) |
 CGI-BP |  |  |
  Depression | 4.23 (0.73) | 4.35 (0.75) |
  Mania | 1.02 (0.14) | 1.03 (0.17) |
  Bipolar | 4.10 (0.87) | 4.17 (0.86) |