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Table 16 Subgroup analysis for study design (ITT vs. completers’ analysis)

From: Antidepressants in the treatment of depression/depressive symptoms in cancer patients: a systematic review and meta-analysis

Author

Year

Drug

Verum

Placebo

 

Participants

Responders

Participants

Responders

Group A: Analyses by ITT

Costa

1985

Mianserin

36

28

37

18

Van Heeringen

1996

Mianserin

28

19

27

10

Musselmann

2006

Paroxetine/desipramine

24

11

11

6

Total

  

88

58

75

34

Group B: analyses not by ITT

Fisch

2003

Fluoxetine

64

31

65

23

Razavi

1996

Fluoxetine

45

8

46

9

Total

  

109

39

111

32

  1. ITT: intention to treat.
  2. RR(A) = 1.49, RR (B) = 1.27 (Zdiff= 0.93, p= 0.36).