Table 1 Baseline and demographic characteristics
Characteristic | LY2140023 | SOC | pValue* |
|---|---|---|---|
(N = 130) | (N = 131) | ||
Age, years, mean (SD) | 38.7 (10.9) | 39.5 (12.5) | .579 |
Gender – female, n (%) | 45 (34.6) | 44 (33.6) | .897 |
Race, n (%) | - | - | .669 |
American Indian or Alaska Native | 20 (15.4) | 18 (13.7) | - |
Black/African American | 44 (33.8) | 39 (29.8) | - |
Multiple | 1 (0.8) | 3 (2.3) | |
White | 65 (50.0) | 71 (54.2) | - |
Diagnosis, n (%) | - | - | .202 |
Catatonic | 1 (0.8) | 0 (0.0) | - |
Disorganized | 8 (6.2) | 4 (3.1) | - |
Paranoid | 100 (76.9) | 109 (83.2) | - |
Residual | 7 (5.4) | 2 (1.5) | |
Undifferentiated | 14 (10.8) | 16 (12.2) | - |
Weight, kg, mean (SD) | 83.0 (21.5) | 82.7 (21.7) | .907 |
Age of first episode, years, mean (SD) | 24.6 (8.3) | 23.1 (8.5) | .148 |
Episodes in the last 24 months, mean (SD) | 1.8 (1.6) | 2.0 (2.1) | .297 |
CGI-S, mean (SD) | 3.8 (0.7) | 3.7 (0.6) | .943 |
PANSS total, mean (SD) | 85.6 (14.8) | 85.1 (15.8) | .788 |
PANSS positive, mean (SD) | 17.6 (4.7) | 18.1 (4.8) | .355 |
PANSS negative, mean (SD) | 26.2 (4.9) | 25.7 (5.2) | .403 |
PANSS general psychopathology, mean (SD) | 41.9 (9.1) | 41.4 (9.3) | .644 |
Negative Assessment Scale-16, mean (SD) | 58.7 (11.0) | 57.3 (11.3) | .336 |