Table 2 Factors associated with relapse during the 24 months of follow-up in the multivariate Cox proportional-hazards models: Adjusted Hazard Ratio (HR) and its corresponding 95% confidence interval (95% CI)
From: Quality of life is predictive of relapse in schizophrenia
SF-36 Model | QoLI Model | |||||
|---|---|---|---|---|---|---|
HR | 95% IC | p-value | HR | 95% IC | p-value | |
Quality of life | ||||||
SF36 - Physical Composite Score * | 0.82 | (0.74;0.91) | p < 0.001 | - | - | - |
SF36 - Mental Composite Score ** | 0.88 | (0.81;0.96) | p = 0.002 | - | - | - |
QoLI - OLS score*** | - | - | - | 0.91 | (0.81;1.01) | p = 0.083 |
Socio-demographic characteristics | ||||||
Age | 0.98 | (0.98;0.99) | p = 0.001 | 0.98 | (0.98;0.99) | p < 0.001 |
Gender (Male) | 1.06 | (0.88;1.30) | p = 0.532 | 1.12 | (0.93;1.34) | p = 0.249 |
Severity of symptoms: PANSS1 | ||||||
Positive PANSS score | 0.99 | (0.97;1.02) | p = 0.514 | 0.99 | (0.97;1.02) | p = 0.560 |
Negative PANSS score | 1.01 | (0.99;1.03) | p = 0.248 | 1.00 | (0.98;1.02) | p = 0.969 |
General Psychopathology PANSS score | 0.99 | (0.97;1.01) | p = 0.419 | 1.00 | (0.98;1.02) | p = 0.937 |
Functioning | ||||||
GAF2 | 0.98 | (0.97;0.99) | p < 0.001 | 0.98 | (0.97;0.99) | p < 0.001 |
Side Effects | ||||||
BAS3 | 0.99 | (0.95;1.02) | p = 0.497 | 1.00 | (0.97;1.03) | p = 0.844 |
Medication | ||||||
Second-generation antipsychotics (Yes) | 1.07 | (0.88;1.29) | p = 0.508 | 1.13 | (0.94;1.36) | p = 0.195 |
Attitude towards medication: ROMI4 | ||||||
ROMI compliance score | 0.97 | (0.94;0.99) | p = 0.041 | 0.97 | (0.95;1.00) | p = 0.063 |