Table 3 Medication discontinuation, hospitalization patterns and concomitant medication utilization in RLAI* and FGAI treatment groups
Outcome | RLAI (n = 70) | FGAI (n = 102) | P value |
|---|---|---|---|
Discontinuation | |||
Proportion of patients discontinued (n (%)) | 11 (15.7) | 13 (12.7) | 0.30 |
Mean time to discontinuation (Months ± SD) | 7.2 ± 5.4 | 7.9 ± 4.8 | 0.99 |
Reason for discontinuation (n (%)) | |||
Patient choice | 7 (63.6) | 5 (38.5) | 0.22 |
Intolerability | 2 (18.2) | 4 (30.8) | 0.65 |
Treatment failure | 2 (18.2) | 0 (0) | 0.20 |
Unknown | 0 (0) | 4 (30.8) | 0.49 |
Hospitalization | |||
Proportion of patients hospitalized (n (%)) | 10 (14.3) | 13 (12.7) | 0.09 |
Mean time to hospitalization (Months ± SD) | 5.4 ± 2.8 | 5.8 ± 5.1 | 0.80 |
Mean duration of hospitalization (Days ± SD) | 35 ± 24 | 29 ± 17 | 0.49 |
Reason for hospitalization (n (%)) | |||
Treatment failure | 10 (100) | 13 (100) | 1.00 |
Concomitant medications (n (%)) | |||
Additional antipsychotic | 21 (30) | 42 (41.1) | 0.14 |
Anticholinergic | 4 (5.7) | 36 (35.3) | <0.001 |
Mood stabilizer | 13 (18.6) | 11 (10.8) | 0.15 |
Antidepressant | 10 (14.3) | 26 (25.5) | 0.08 |
Benzodiazepine | 7 (10.0) | 9 (8.8) | 0.79 |