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Table 5 Determinants of significant risk factors associated with post-stroke apathy (n = 75)

From: Predictors of early post ischemic stroke apathy and depression: a cross-sectional study

 

Univariate

Multivariate

 

OR (95% CI)

p-value

OR (95% CI)

p-value

Age (yrs)

1.08 (1.02, 1.15)

0.011*

  

Gender

    

 Female vs. Male

1.19 (0.44, 3.18)

0.736

  

Education (yrs)

0.87 (0.77, 0.98)

0.021*

  

Frontal

    

 Yes vs. no

3.69 (1.30, 10.52)

0.014*

  

Temporal

    

 Yes vs. no

3.63 (0.92, 14.34)

0.066

  

Parietal

    

 Yes vs. no

0.38 (0.04, 3.40)

0.383

  

Occipital

    

 Yes vs. no

0.48 (0.05, 4.53)

0.521

  

Basal ganglia

    

 Yes vs. no

1.10 (0.38, 3.18)

0.858

  

Cerebellum

    

 Yes vs. no

0.48 (0.05, 4.53)

0.521

  

Brain stem

    

 Yes vs. no

1.67 (0.62, 4.49)

0.309

  

Corona radiata

    

 Yes vs. no

1.63 (0.55, 4.84)

0.378

  

Cerebrovascular disease

    

 Yes vs. no

2.63 (0.96, 7.20)

0.060

6.45 (1.48, 28.05)

0.013*

Hypertension

    

 Yes vs. no

0.55 (0.20, 1.48)

0.232

  

Diabetes mellitus

    

 Yes vs. no

0.54 (0.16, 1.88)

0.334

  

Smoking

    

 Yes vs. no

1.27 (0.49, 3.33)

0.624

  

Drinking

    

 Yes vs. no

1.49 (0.52, 4.31)

0.462

  

SBP (mmHg)

0.99 (0.96, 1.01)

0.214

  

DBP (mmHg)

0.96 (0.93, 1.00)

0.059

  

Heart rate (bpm)

0.99 (0.95, 1.03)

0.610

  

Total cholesterol (mmol/L)

0.71 (0.40, 1.24)

0.226

  

Triglycerides (mmol/L)

0.49 (0.22, 1.07)

0.074

  

LDL-C (mmol/L)

0.69 (0.32, 1.48)

0.335

  

HDL-C (mmol/L)

0.61 (0.11, 3.39)

0.572

  

HbA1c (%)

0.44 (0.20, 0.97)

0.043*

0.31 (0.12, 0.81)

0.017*

NIHSS

1.06 (0.86, 1.30)

0.606

  

MMSE score

0.77 (0.66, 0.90)

0.001*

  

MoCA score

0.85 (0.77, 0.95)

0.003*

  

MDRS I/P

0.85 (0.76, 0.94)

0.001*

0.84 (0.74, 0.96)

0.010*

FAB

0.87 (0.75, 1.00)

0.057

  

HAMD

1.13 (1.00, 1.27)

0.059

  

Stroop color-naming

    

 B-Atime

1.01 (1.00, 1.02)

0.211

  

 B-Anumber

0.94 (0.88, 1.01)

0.087

  
  1. *Significance factor, p < 0.05.
  2. Abbreviations: SBP Systolic blood pressure, DBP Diastolic blood pressure, LDL-C Low-density lipoprotein cholesterol, HDL-C High-density lipoprotein cholesterol, HbA1c Hemoglobin A1c, NIHSS National Institutes of health stroke scale, MMSE Mini-mental state examination, MoCA Montreal cognitive assessment, MDRS I/P Mattis dementia rating scale initiation/preservation subset, FAB Frontal assessment battery, HAMD Hamilton depression scale.