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Table 2 Differences between interventions to prevent the onset of depression evaluated so far in adults and the new intervention in primary care

From: Preventing the onset of major depression based on the level and profile of risk of primary care attendees: protocol of a cluster randomised trial (the predictD-CCRT study)

Characteristics Other interventions New intervention
Type of prevention Selective or indicated1 Universal 2
Orientation Psychosocial (cognitive-behavioral, interpersonal…) or psychoeducational Biopsychosocial (primary care orientation) and based on level and risk profile of becoming depressed (personalized)
Type of intervention Formal (fixed rules) Not formal (tailored rules)
Same number of sessions for all patients Minimum of three interviews but no maximum
Same components for all patients Number of components involved tailored
Who implements the intervention? Therapists or specialists in mental health (psychologist, psychiatric nurse…) Family physicians
Sample size Small Large
  1. 1 Patients with a specific risk of depression, high risk or subclinically depressed.
  2. 2 Patients with a low, moderate or high risk of depression. To date universal interventions have been evaluated to prevent depression but only in children and adolescents.