Skip to main content

Table 2 Biological factors and medication as correlates of long-term life dissatisfaction burden 1) in linear regression models

From: Biological and other health related correlates of long-term life dissatisfaction burden

Variables

Bivariate model2)B (95% CI)

p-value2)

Multivariate model 23)B (95% CI)

p-value3)

Age

−0.002 (−0.004–0.000)

0.014

−0.001 (−0.003 – 0.001)

ns

Gender (male)

0.018 (−0.016–0.051)

ns

0.029 (−0.005 – 0.064)

ns

Metabolic syndrome (yes)

0.038 (0.004–0.073)

0.030

0.046 (0.010 – 0.081)

0.012

Use of statins (yes)

−0.062 (−0.100– -0.023)

0.002

−0.064 (−0.106 – -0.023)

0.002

Adiponectin, [μg/ml]

−0.001 (−0.002–0.000)

0.016

−0.001 (−0.002 – 0.000)

0.023

Coronary heart disease (yes)

−0.004 (−0.064 – 0.057)

ns

Nim

Nim

Rheumatoid arthritis (yes)

0.041 (−0.025 – 0.106)

ns

Nim

Nim

Hypertension (yes)

0.016 (−0.020 – 0.052)

ns

Nim

Nim

Use of oral corticosteroids (yes)

0.056 (−0.042 – 0.153)

ns

Nim

Nim

Use of NSAIDs (yes)

−0.003 (−0.096 – 0.090)

ns

Nim

Nim

BMI, [kg/m2]

0.003 (0.000–0.006)

ns

Nim

Nim

Resistin, [ng/ml]

0.000 (−0.002 – 0.002)

ns

Nim

Nim

hs-CRP, [mg/l]

−0.001 (−0.004 – 0.002)

ns

Nim

Nim

TNF-α, [pg/ml]

0.000 (0.000–0.000)

ns

Nim

Nim

IL6, [pg/ml]

0.000 (0.000–0.001)

ns

Nim

Nim

  1. 1)Long-term life dissatisfaction burden score: sum of life satisfaction scores in 1998, 1999, 2001 and 2005 with logarithmic transformation.
  2. 2)Bivariate linear regression analysis separately for each variable.
  3. 3)Multiple adjusted linear model 2 (method: enter) included the following factors: age (continuous), gender (0 = female, 1 = male), metabolic syndrome (0 = no, 1 = yes), use of statins (0 = no, 1 = yes), and serum adiponectin level (continuous).
  4. Nim = not included in the model due to nonsignificant association in the bivariate model.
  5. Abbreviations: NSAID Non-steroidal anti-inflammatory drug, BMI Body mass index, hs-CRP High-sensitivity C-reactive protein, TNF-α Tumor Necrosis Factor α, IL6 Interleukin 6.