Table 4 Sociodemographic, health behavior, and biological factors in 2005 by two-category long-term life dissatisfaction burden score

Gender (male), n (%)

42.1

(67)

43.2

(63)

ns

Living alone, n (%)

7.5

(12)

21.9

(32)

<0.001

Smoking (yes), n (%)

8.2

(13)

29.5

(43)

<0.001

Alcohol consumption ≥2/week, n (%)

16.4

(26)

19.9

(29)

ns

Social support (poor)

1.3

(2)

24.1

(36)

<0.001 ³⁾

Sleep (poor), n (%)

42.8

(68)

69.2

(101)

<0.001

Metabolic syndrome, n (%)²⁾

31.2

(48)

43.4

(63)

0.028

Hypertension, n (%)

28.9

(46)

32.2

(47)

ns

Coronary heart disease, n (%)

7.5

(12)

8.9

(13)

ns

Rheumatoid arthritis, n (%)

6.3

(10)

7.5

(11)

ns

Cancer, n (%)

1.3

(2)

2.7

(4)

ns³⁾

Use of oral corticosteroids, n (%)

2.5

(4)

3.4

(5)

ns³⁾

Use of NSAIDs, n (%)

4.4

(7)

2.1

(3)

ns³⁾

Use of statins, n (%)

30.2

(48)

16.4

(24)

0.005

Variables

Mean (95% CI)

Mean (95% CI)

p-value

Age ⁴⁾

56.9 (55.3–58.6)

55.1 (53.6–56.6)

0.025 ⁵⁾

BMI, [kg/m²]⁴⁾

27.1 (26.4–27.9)

27.8 (26.8–28.8)

ns⁵⁾

Adiponectin, [μg/ml]⁴⁾

18.39 (15.59–21.19)

13.38 (11.44–15.31)

0.014 ⁵⁾

Resistin, [ng/ml]⁴⁾

10.26 (9.22–11.31)

11.62 (9.99–13.25)

ns⁵⁾

hs-CRP, [mg/l]⁴⁾

2.76 (2.08–3.44)

3.14 (2.43–3.85)

ns⁵⁾

TNF-α, [pg/ml]⁴⁾

11.03 (4.28–17.78)

11.57 (3.69–19.46)

ns⁵⁾

IL6, [pg/ml]⁴⁾

3.53 (2.05–5.01)

4.35 (2.15–6.56)

ns⁵⁾