| |
Bipolar I disorder (N = 32)
|
Bipolar II disorder (N = 81)
|
|---|
| |
Hypomania
|
Depression
|
Euthymia
|
Hypomania
|
Depression
|
Euthymia
|
|---|
| |
N = 7
|
N = 18
|
N = 7
|
N = 18
|
N = 47
|
N = 16
|
|---|
| |
N (%)
|
N (%)
|
N (%)
|
N (%)
|
N (%)
|
N (%)
|
|---|
|
Lithium
|
4 (57.1)
|
11 (61.1)
|
5 (71.4)
|
3 (16.7)
|
8 (17.0)
|
4 (25.0)
|
|
Anticonvulsants
|
2 (28.6)
|
5 (27.8)
|
3 (42.9)
|
7 (38.9)
|
25 (53.2)
|
4 (25.0)
|
|
Antidepressants
|
3 (42.9)
|
13 (72.2)
|
1 (14.3)
|
10 (55.6)
|
34 (72.3)
|
10 (62.5)
|
|
Neuroleptics
|
3 (42.9)
|
11 (61.1)
|
4 (57.1)
|
7 (38.9)
|
20 (42.6)
|
6 (37.5)
|
|
First generation
|
0
|
1 (5.6)
|
1 (14.3)
|
1 (5.6)
|
3 (6.4)
|
0
|
|
Second generation
|
3 (42.9)
|
11 (61.1)
|
3 (42.9)
|
6 (33.3)
|
18 (38.3)
|
6 (37.5)
|
|
Benzodiazepines
|
0
|
7 (38.9)
|
3 (42.9)
|
3 (16.7)
|
8 (17.0)
|
5 (31.3)
|
|
At least one MS or AAP in therapeutic range*
|
7 (100)
|
15 (83.3)
|
5 (71)
|
8 (44.4)
|
26 (55.3)
|
6 (37.5)
|
|
At least one psychotropic drug
|
7 (100)
|
18 (100)
|
7 (100)
|
16 (88.9)
|
44 (93.6)
|
13 (81.3)
|
- *MS or AAP in therapeutic range: lithium serum levels ≥0.5 mEq/L; valproate ≥750 mg daily; carbamazepine ≥600 mg daily; lamotrigine ≥50 mg daily; olanzapine ≥5 mg daily; risperidone ≥2 mg daily; quetiapine ≥150 mg daily.
