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Table 3 Classes of psychotropic treatment by type of bipolar disorder and nature of current mood episode

From: Pharmacotherapy for bipolar disorder and concordance with treatment guidelines: survey of a general population sample referred to a tertiary care service

 

Bipolar I disorder (N = 32)

Bipolar II disorder (N = 81)

 

Hypomania

Depression

Euthymia

Hypomania

Depression

Euthymia

 

N = 7

N = 18

N = 7

N = 18

N = 47

N = 16

 

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

Lithium

4 (57.1)

11 (61.1)

5 (71.4)

3 (16.7)

8 (17.0)

4 (25.0)

Anticonvulsants

2 (28.6)

5 (27.8)

3 (42.9)

7 (38.9)

25 (53.2)

4 (25.0)

Antidepressants

3 (42.9)

13 (72.2)

1 (14.3)

10 (55.6)

34 (72.3)

10 (62.5)

Neuroleptics

3 (42.9)

11 (61.1)

4 (57.1)

7 (38.9)

20 (42.6)

6 (37.5)

First generation

0

1 (5.6)

1 (14.3)

1 (5.6)

3 (6.4)

0

Second generation

3 (42.9)

11 (61.1)

3 (42.9)

6 (33.3)

18 (38.3)

6 (37.5)

Benzodiazepines

0

7 (38.9)

3 (42.9)

3 (16.7)

8 (17.0)

5 (31.3)

At least one MS or AAP in therapeutic range*

7 (100)

15 (83.3)

5 (71)

8 (44.4)

26 (55.3)

6 (37.5)

At least one psychotropic drug

7 (100)

18 (100)

7 (100)

16 (88.9)

44 (93.6)

13 (81.3)

  1. *MS or AAP in therapeutic range: lithium serum levels ≥0.5 mEq/L; valproate ≥750 mg daily; carbamazepine ≥600 mg daily; lamotrigine ≥50 mg daily; olanzapine ≥5 mg daily; risperidone ≥2 mg daily; quetiapine ≥150 mg daily.