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Table 3 Odor naming is associated with cognition and odor interpretation with severity of positive symptoms and alertness in schizophrenia subjects (N=881)

From: Odor naming and interpretation performance in 881 schizophrenia subjects: association with clinical parameters

  Odor naminga Odor interpretationa
Higher cognition compositeb 0.165 0.057
(t 813 = 2.347, p=0.019) (t814= 0.789, p=0.430)
Alertness (TAP) 0.144 0.196
(t 813 = 3.401, p=0.001) (t 814 = 4.635, p=0.000)
PANSS negative −0.112 −0.045
(t 813 =−2.717, p=0.007) (t814=−1.073, p=0.283)
PANSS positive −0.055 −0.107
(t813=−1.407, p=0.160) (t 814 =−2.701, p=0.007)
Fine motor function compositec,d −0.010 0.017
(t813=−0.210, p=0.834) (t814= 0.336, p=0.737)
Premorbid intelligence (MWTB)d 0.071 0.059
(t813= 1.761, p=0.079) (t814= 1.420, p=0.156)
  1. aRelative association strength of domains with odor naming and odor interpretation (t-statistic tdf with df degrees of freedom, p value). Multiple linear regression model containing linear terms for all six predictor variables (table rows) and adjusting for age (odor naming and odor interpretation) and gender (odor naming), significances (Bonferroni p≤0.025) in boldface. bThe higher cognition composite includes the following cognitive domains: Reasoning ability (subtest 3 of the Leistungsprüfsystem, a German test covering Thurstone’s primary mental abilities), executive functioning (difference of execution times between Trail Making Test A and B), working memory (Letter Number Sequencing), processing speed (Digit Symbol Coding), verbal memory (Verbal Learning and Memory Test) and divided attention (test battery for attention). cThe fine motor function composite consists of dotting and tapping subtests of the MacQuarrie test for mechanical ability. dControl variables.