Skip to main content

Table 1 Characterization of study population receiving treatment with an antipsychotic medication

From: A retrospective study of antipsychotic drug switching in a pediatric population

  Depressive disorder Anxiety Attention-deficit hyperactivity disorder Psychosis Bipolar disorder Substance abuse Autism Tics/Neurological disorder
Subjects (M/F) 19 (6/13) 35 (27/8) 35 (26/9) 14 (8/6) 12 (6/6) 3 (2/1) 18 (12/6) 2 (2/0)
Mean Age (SD) 15.05 (1.92) 11.10 (2.81) 10.45 (2.60) 15.65 (1.25) 13.07 (3.22) 15.76 (0.54) 12.42 (3.17) 10.41 (2.21)
Risperidone (% of Dx group) 3 (15.8) 14 (40.0) 17 (48.6) 5 (35.7) 1 (8.3) 0 (0.0) 7 (38.9) 0 (0.0)
Mean Dose mg (SD) 0.92 (0.63) 0.89 (0.50) 1.01 (0.50) 2.20 (1.10) 1.00 0 1.54 (1.10) 0
Olanzapine (% of Dx group) 5 (26.3) 0 (0.0) 0 (0.0) 5 (35.7) 0 (0.0) 0 (0.0) 3 (16.7) 0 (0.0)
Mean Dose mg (SD) 6.00 (1.37) 0 0 15.00 (3.54) 0 0 11.67 (2.89) 0
Quetiapine (% of Dx group) 7 (36.8) 11 (31.4) 7 (20.0) 5 (35.7) 8 (66.7) 0 (0.0) 5 (27.8) 1 (50.0)
Mean Dose mg (SD) 251.79 (195.31) 138.64 (128.51) 89.29 (34.93) 325.00 (269.26) 276.56 (208.14) 0 160.00 (96.18) 75
Ziprasidone (% of Dx group) 0 (0.0) 0 (0.0) 1 (2.9) 1 (7.1) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Mean Dose mg (SD) 0 0 40 20 0 0 0 0
Aripiprazole (% of Dx group) 0 (0.0) 0 (0.0) 0 (0.0) 1 (7.1) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Mean Dose mg (SD) 0 0 0 7.5 0 0 0 0
FGAs (% of Dx group) 2 (10.5) 0 (0.0) 0 (0.0) 2 (14.3) 0 (0.0) 0 (0.0) 1 (5.6) 0 (0.0)
Mean Dose mg (SD) - - - - - - - -
CPZ Equiv mg (SD) 220.60 (217.14) 110.76 (134.21) 73.44 (54.30) 316.07 (253.32) 333.33 (280.50) 0 186.01 (185.73) 100.00
# Emergency Visits (SD) 0.58 (0.77) 0.66 (1.37) 0.74 (1.77) 0.79 (1.19) 0.33 (0.78) 1.67 (1.15) 0.78 (2.07) 1.50 (2.12)
Switched Pre Hosp (% of Dx group) 7 (36.8) 5 (14.3) 6 (17.1) 1 (7.1) 3 (25.0) 1 (33.3) 2 (11.1) 1 (50.0)
Switched Post Hosp (% of Dx group) 0 (0.0) 0 (0.0) 1 (2.9) 4 (28.6) 1 (8.3) 0 (0.0) 0 (0.0) 0 (0.0)
  1. 139 patients were identified who had been treated with an antipsychotic drug either during hospital admission or in the 52 weeks prior to admission. Table indicates characteristics of groups based on different psychiatric diagnosis at time of discharge. FGA = First Generation Antipsychotic; CPZ = Chlorpromazine.