Table 1 Characterization of study population receiving treatment with an antipsychotic medication
From: A retrospective study of antipsychotic drug switching in a pediatric population
| Â | Depressive disorder | Anxiety | Attention-deficit hyperactivity disorder | Psychosis | Bipolar disorder | Substance abuse | Autism | Tics/Neurological disorder |
|---|---|---|---|---|---|---|---|---|
Subjects (M/F) | 19 (6/13) | 35 (27/8) | 35 (26/9) | 14 (8/6) | 12 (6/6) | 3 (2/1) | 18 (12/6) | 2 (2/0) |
Mean Age (SD) | 15.05 (1.92) | 11.10 (2.81) | 10.45 (2.60) | 15.65 (1.25) | 13.07 (3.22) | 15.76 (0.54) | 12.42 (3.17) | 10.41 (2.21) |
Risperidone (% of Dx group) | 3 (15.8) | 14 (40.0) | 17 (48.6) | 5 (35.7) | 1 (8.3) | 0 (0.0) | 7 (38.9) | 0 (0.0) |
Mean Dose mg (SD) | 0.92 (0.63) | 0.89 (0.50) | 1.01 (0.50) | 2.20 (1.10) | 1.00 | 0 | 1.54 (1.10) | 0 |
Olanzapine (% of Dx group) | 5 (26.3) | 0 (0.0) | 0 (0.0) | 5 (35.7) | 0 (0.0) | 0 (0.0) | 3 (16.7) | 0 (0.0) |
Mean Dose mg (SD) | 6.00 (1.37) | 0 | 0 | 15.00 (3.54) | 0 | 0 | 11.67 (2.89) | 0 |
Quetiapine (% of Dx group) | 7 (36.8) | 11 (31.4) | 7 (20.0) | 5 (35.7) | 8 (66.7) | 0 (0.0) | 5 (27.8) | 1 (50.0) |
Mean Dose mg (SD) | 251.79 (195.31) | 138.64 (128.51) | 89.29 (34.93) | 325.00 (269.26) | 276.56 (208.14) | 0 | 160.00 (96.18) | 75 |
Ziprasidone (% of Dx group) | 0 (0.0) | 0 (0.0) | 1 (2.9) | 1 (7.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Mean Dose mg (SD) | 0 | 0 | 40 | 20 | 0 | 0 | 0 | 0 |
Aripiprazole (% of Dx group) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (7.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Mean Dose mg (SD) | 0 | 0 | 0 | 7.5 | 0 | 0 | 0 | 0 |
FGAs (% of Dx group) | 2 (10.5) | 0 (0.0) | 0 (0.0) | 2 (14.3) | 0 (0.0) | 0 (0.0) | 1 (5.6) | 0 (0.0) |
Mean Dose mg (SD) | - | - | - | - | - | - | - | - |
CPZ Equiv mg (SD) | 220.60 (217.14) | 110.76 (134.21) | 73.44 (54.30) | 316.07 (253.32) | 333.33 (280.50) | 0 | 186.01 (185.73) | 100.00 |
# Emergency Visits (SD) | 0.58 (0.77) | 0.66 (1.37) | 0.74 (1.77) | 0.79 (1.19) | 0.33 (0.78) | 1.67 (1.15) | 0.78 (2.07) | 1.50 (2.12) |
Switched Pre Hosp (% of Dx group) | 7 (36.8) | 5 (14.3) | 6 (17.1) | 1 (7.1) | 3 (25.0) | 1 (33.3) | 2 (11.1) | 1 (50.0) |
Switched Post Hosp (% of Dx group) | 0 (0.0) | 0 (0.0) | 1 (2.9) | 4 (28.6) | 1 (8.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) |