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Table 2 Meta-analysis of case–control studies on the role of the T and C alleles in the T102C polymorphism of the 5HTR2A gene in individuals with suicidal behavior

From: Association of the 5HTR2A gene with suicidal behavior: CASE-control study and updated meta-analysis

References

Number of T alleles

Number of C alleles

Odds Ratio (95%IV)

 

Cases

Controls

Cases

Controls

T Allele

C Allele

Correa

91

41

83

43

1.14 (0.68 - 1.93)

1.14 (0.68 - 1.93)

Wrzosek

24

87

33

133

1.11(0.61 - 2.00)

1.11( 0.61 – 2.00)

Zhang

287

303

229

265

1.09 (0.86 - 1.39)

1.09 ( 0.86 - 1.39)

Vadim

54

69

54

57

0.82 (0.49 – 1.38)

0.82 ( 0.49 - 1.38)

Du

57

134

99

128

0.55 (0.36 - 0,8254)

1.13 (0.50 - 2.53)

Vaquero-Lorenzo

410

422

472

398

0.81(0.67- 0.99)

0.81 ( 0.67- 0.99)

Du

16

19

32

43

1.13( 0.50 - 2.53)

0.55 ( 0.36 – 0.82)

Bondy

120

112

142

138

1.04 ( 0.73- 1.47)

1.04 (0.73 - 1.47)

Zhang

9

159

21

141

1.09 (0.86 - 1.39)

1.09 (0.86 - 1.39)

Arias

24

141

42

187

0.75 ( 0.43 - 1.30)

0.38 ( 0.16 - 0.85)

Tsai

73

122

49

70

0.85 ( 0.53 - 1.36)

0.85( 0.53 - 1.36)

Turecki

40

108

68

34

0.18 (0.10 - 0.32)

0.18 ( 0.10 - 0.32)

Preuss

38

107

52

127

0.86 ( 0.53 - 1.41)

0.55 ( 0.36 - 0.82)

Preuss

58

107

66

127

1.04 ( 0.67 - 1.61)

1.04 (0.67 – 1.61)

Crawford

63

68

73

122

1.54 ( 0.98 - 2.42)

1.54 ( 0.98 - 2.42)

Crawford

57

134

99

128

0.55 ( 0.36 - 0.82)

0.55 ( 0.36 – 0.82)

Ertugrul

39

27

49

27

0.79 ( 0.40 - 1,56)

0.79 (0.40 - 1.56)

Tan

62

126

32

62

0.95 ( 0.56 - 1.60)

0.95 (0.56 - 1.60)

Pooley

104

249

154

409

1.10 ( 0.82 - 1.48)

1.10 (0.82 - 1.48)

Chen

435

694

193

352

1.14 (0.92- 1.41)

1.14 (0.92 - 1.41)

Tovilla

102

118

220

370

1.45 ( 1.06 - 1.98)

1.45 (1.06 - 1.98)

Ono

145

169

157

157

  

Saiz

190

378

196

462

  

Random effects

2498

3894

2615

3980

0.87 ( 0.73 – 1.03)

0.87(0.73 - 1.03)