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Table 1 Neuroimaging acquisition sequences

From: Multimodal neuroimaging of frontal white matter microstructure in early phase schizophrenia: the impact of early adolescent cannabis use

Type

Parameters

Min

Localizer and calibration

 

2

3D SPGR T1-weighted, for online placement of VOI and its offline tissue segmentation

256 x 256 matrix; 170 sagittal slices; 1 mm isotropic resolution, no inter-slice gap; TR = 11.3 s; TE = 4.2 ms; flip angle = 20 deg.

7

1H-MRS volume of interest (VOI)

Online VOI placement; shimming (values are carried over to each subsequent 1H-MRS acquisition)

6

NAA concentration levels and T2 time constants of NAA

PRESS; TR = 3 s; TEs = 80, 120, 180, 350, 600 ms; NEX = 64

25

T2 time constants of water

TR = 10 s; TEs = 50, 60, 80, 120, 180, 350, 600, 800, 1000 ms; NEX = 4

20

Diffusion-weighted images

TR = 8.5 s; TE 80–90 ms; flip angle = 90 deg; 54 non-collinear diffusion weighting directions, b-factor of 1000 s/mm2; 6 acquisitions, b-factor of ~ 0 s/mm2; 256 x 256 matrix; 260 FOV; 1.02 x 1.02 x 3 mm3 voxels; NEX = 1; acquisition of field maps.

25