Dysregulation of leukocyte gene expression in women with medication-refractory depression versus healthy non-depressed controls

Table 1 Candidate genes for mRNA gene expression in DD

Pathways	Classes	Genes
HPA	Glucocorticoid	NR3C1
	Mineralocorticoid	NR3C2
	Oxytocin	OXT
	Oxytocin receptor	OXTR
Immune response and inflammation	Cytokines	IL-10, IL-6, TNF, LTA
Transcription factors	Gene expression factors	CREB1, SIRT1, STAT5A, PPARA, NFκB1
Neuronal health and signaling	Growth factors	NRG1, VEGFA
	Matrix associated	APP, SPARC
	Modulator	DBI
Ion channels	Purinergic	P2RX1, P2RX4, P2RX7, P2RY1,
	Acid sensing	P2RY2
	Transient	ASIC1, ASIC3
	Vanilloid	TRPV1, TRPV4

ISSN: 1471-244X