Brain responses to body image stimuli but not food are altered in women with bulimia nervosa

BMC Psychiatry

Table 3 Body image paradigm: group map activations in the bulimia nervosa (BN) and healthy control (HC) groups, and between-group differences in brain activation patterns for the contrast ‘body image vs low level baseline (LLB)’

	Hemisphere	Brodmann area (BA)	Talairach coordinates	Cluster size (voxels)
People with BN
*Body image > LLB*
R Middle frontal gyrus	< 0.001	BA9	x = 50.7; y = 7.4; z = 36.3	189
R Thalamus (pulvinar)	0.005		x = 25.3; y = -29.6; z = 3.3	42
L Inferior parietal lobe	0.004	BA40	x = -39.7; y = -40.7; z = 42.9	76
R Cerebellum, declive	< 0.001		x = 36.1; y = -55.6; z = -16.5	2259
*LLB > Body image*
L Middle frontal gyrus	< 0.001	BA8	x = -28.9; y = 18.5; z = 42.9	689
R Frontal paracentral lobule	< 0.001	BA5	x = 18.1; y = -37; z = 49.5	410
R Cerebellum, culmen	< 0.001		x = 3.6; y = -40.7; z = -19.8	2706
HCs
*Body image > LLB*
R Middle frontal gyrus	< 0.001	BA9	x = 43.3; y = 11.1; z = 23.1	216
L Inferior frontal gyrus	0.005	BA6	x = -43.3; y = 0.0; z = 33.0	65
R Superior frontal gyrus	0.001	BA9	x = 3.6; y = 59.3; z = 33.0	158
R Inferior occipital	0.002	BA19	x = 39.7; y = -7.0; z = -6.6	2546
*LLB > Body image*
L Cerebellum, culmen	0.002		x = -10.8; y = -44.4; z = -19.8	8199
People with BN vs HCs
*People with BN > HCs*
R Insula	0.002	BA13	x = 36.1; y = -18.5; z = -16.5	103
L Cerebellum, anterior lobe	0.003		x = -3.6; y = -55.6; z = -23.1	103
*HCs > People with BN*
R Fusiform gyrus	< 0.001	BA37	x = 39.7; y = -66.7; z = -13.2	288
L Middle occipital cortex	< 0.001	BA19	x = 46.9; y = -63.0; z = -9.9	156
L Parietal cortex, precuneus	0.006	BA7	x = -21.7; y = -59.3; z = 39.6	47
R Parietal cortex, precuneus	0.006	BA7	x = 25.3; y = -55.6; z = 46.2	42

The Talairach coordinates indicate the location of the peak voxel within each cluster.

ISSN: 1471-244X