Brain responses to body image stimuli but not food are altered in women with bulimia nervosa

BMC Psychiatry

Table 4 Food paradigm: group map activations in the bulimia nervosa (BN) and healthy control (HC) groups, and between-group differences in brain activation patterns for the contrast ‘food vs non-food’

	p-value	Brodmann area (BA)	Talairach coordinates	Cluster size (voxels)
People with BN
*Food > Non-Food*
R Lingual Gyrus	< 0.001	18	x = 14.4; y = -81.5; z = -9.9	710
R Thalamus (Pulivinar)	< 0.001	-	x = 10.8; y = -22.2; z = -6.6	68
R Anterior Cingulate	< 0.001	32	x = 3.6; y = 44.4; z = 6.6	203
*Non-Food > Food*
R Cerebellum, Culmen	< 0.001	-	x = 10.8; y = -33.3; z = -13.2	191
L Precuneus	< 0.001	7	x = -3.6; y = -55.6; z = 29.7	40
R Middle Temporal Gyrus	0.002	21	x = 50.6; y = 0.0; z = -19.8	1578
L Middle Temporal Gyrus	< 0.001	37	x = -50.6; y = -55.6; z = 3.3	2063
HCs
*Food > Non-Food*
L Frontal Subcallosal Gyrus	0.002	34	x = 21.7; y = 3.7; z = -9.9	80
R Middle Frontal Gyrus	0.004	46	x = 43.3; y = 37.0; z = 19.8	54
R Lingual Gyrus	< 0.001	18	x = 14.4; y = -85.2; z = -3.3	1061
R Superior Parietal Lobule	0.002	7	x = 28.9; y = -55.6; z = 42.9	109
R Middle Frontal Gyrus	0.002	6	x = 43.3; y = 3.7; z = 46.2	72
L Frontal Superior Gyrus	0.001	8	x = -21.7; y = 25.9; z = 49.5	169
*Non-Food > Food*
L Middle Frontal Gyrus	0.001	11	x = -43.3; y = 48.2; z = -13.2	45
L Caudate (Body)	0.002	-	x = -14.4; y = -14.8; z = 3.1	67
L Superior Temporal Gyrus	< 0.001	22	x = -36.1; y = -48.2; z = 9.9	3398
L Middle Frontal Gyrus	< 0.001	46	x = -39.7; y = 25.9; z = 16.5	513
People with BN vs HCs
*People with BN > HCs*
None
*HCs > People with BN*
None

The Talairach coordinates indicate the location of the peak voxel within each cluster.

ISSN: 1471-244X