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Table 2 Baseline characteristics of the total sample of FEP patients and by baseline adherence (good, bad)

From: Cannabis use and involuntary admission may mediate long-term adherence in first-episode psychosis patients: a prospective longitudinal study

Variable

Total sample (N  = 98)

Bad adherence (n  = 73)

Good adherence (n  = 25)

p value

Gender, n (%)

   

Chi2 = 0.003 (p = 0.954)

 Male

71 (72.4)

53 (72.6)

18 (72.0)

 Female

27 (27.6)

20 (27.4)

7 (28.0)

Age

29.8 ± 10.7

29.9 ± 10.2

30.7 ± 12.2

U = 762.5 (p = 0.858)

Civil status, n (%)

   

Chi2 = 2.910 (p = 0.233)

 Single

74 (75.5)

57 (78.1)

17 (68.0)

 Married

17 (17.3)

10 (13.7)

7 (28.0)

 Other

7 (7.2)

6 (8.2)

1 (4.0)

Family history, n (%)

   

Chi2 = 6.036 (p= 0.014)

 No

16 (16.3)

8 (10.9)

8 (32.0)

 Yes

82 (83.7)

65 (89.1)

17 (68.0)

Diagnosis, n (%)

   

Chi2 = 0.601 (p = 0.740)

 Bipolar disorder & affective

33 (33.7)

23 (31.5)

10 (40.0)

 Schizophrenia

39 (39.8)

30 (41.1)

9 (36.0)

 Other

26 (26.5)

20 (27.4)

6 (24.0)

PANSS basal positivea

24.8 ± 6.9

25.0 ± 6.7

24.4 ± 8.0

U = 636.0 (p = 0.640)

PANSS basal negativea

18.9 ± 9.4

18.3 ± 9.1

20.5 ± 9.7

U = 598.0 (p = 0.395)

PANSS basal generala

42.2 ± 11.4

40.6 ± 10.4

47.7 ± 13.1

U = 598.0 (p = 0.395)

GAF basalb

55.5 ± 17.9

58.5 ± 16.2

69.2 ± 14.8

U = 152.5 (p= 0.019)

YMRS basal

25.4 ± 12.1

26.8 ± 12.4

21.6 ± 11.8

U = 494.5 (p = 0.059)

HDRS-21 basal

17.9 ± 8.4

16.4 ± 7.0

22.6 ± 10.9

U = 446.0 (p= 0.017)

Phillips total basalc

5.6 ± 3.0

5.9 ± 2.9

5.2 ± 3.5

U = 587.5 (p = 0.337)

Strauss total basalb

12.8 ± 3.9

12.5 ± 3.7

13.1 ± 4.5

U = 281.5 (p = 0.830)

Aggressiveness, n % yes [vs. no]

73 (74.5)

57 (78.1)

16 (64.0)

Chi2 = 1.943 (p = 0.163)

Tobacco use, n (%) yes [vs. no]

79 (80.6)

61 (83.6)

18 (72.0)

Chi2 = 1.593 (p = 0.207)

Alcohol use, n (%) yes [vs. no]

94 (95.9)

72 (98.6)

22 (88.0)

Chi2 = 5.375 (p= 0.020)

Cannabis use, n (%) yes [vs. no]

51 (52.0)

40 (54.8)

11 (44.0)

Chi2 = 0.869 (p = 0.351)

Other drugs use, n (%) yes [vs. no]

33 (33.7)

25 (34.2)

8 (32.0)

Chi2 = 0.042 (p = 0.837)

Voluntary admission, n (%)

   

Chi2 = 44.749 (p< 0.001)

 No

56 (57.1)

56 (76.7)

0 (0)

 Yes

42 (42.9)

17 (23.3)

25 (100)

  1. Data are presented as mean ± SD or n (%).
  2. Total n varies for the different variables due to missing data. The percentage given for each variable refers to the total n available for that variable.
  3. P values are results of Chi-square (categorical variables) and Mann–Whitney U tests (continuous variables) for the comparison between groups with good versus bad adherence.
  4. Values in bold are significant at p < 0.05.
  5. Note: PANSS, Positive and Negative Symptoms Scale; GAF, Global Assessment of Functioning; YMRS, Young Mania Rating Scale; HDRS-21, Hamilton Depression Rating Scale, Phillips total; Phillips Premorbid adjustment scale total score; Strauss, Strauss-Carpenter prognostic scale score.
  6. aFor PANSS scores, a higher score indicates worse symptoms.
  7. bFor GAF and Strauss, a lower score indicates poorer functioning.
  8. cFor Phillips, a higher score indicates poorer premorbid adjustment.