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Table 4 Changes in ADHD symptoms and WISC-III scores in the two age groups after MPH treatment for one year

From: Long-term effects of stimulants on neurocognitive performance of Taiwanese children with attention-deficit/hyperactivity disorder

 

6-8 years (N = 47)

9-12 years (N = 56)

P value2

Item

Mean ± SD

Sig.1

Mean ± SD

Sig.1

  

ADHDRS_total

−7.0 ± 6.9

***

−8.4 ± 6.6

***

0.351

 

ADHDRS_inattention

−3.6 ± 4.0

***

−4.3 ± 3.5

***

0.332

 

ADHDRS_hyperactivity

−3.5 ± 3.6

***

−4.0 ± 3.8

***

0.526

 

CGI –S

−0.9 ± 0.7

***

−0.9 ± 1.0

***

0.892

 

WISC-III

      

Information

0.4 ± 1.6

 

0.2 ± 1.6

 

0.695

 

Similarities

1.1 ± 2.4

*

−0.1 ± 1.4

 

0.013

*

Arithmetic

0.1 ± 2.4

 

0.1 ± 1.5

 

0.996

 

Vocabulary

0.5 ± 2.2

 

0.2 ± 1.6

 

0.545

 

Comprehension

0.4 ± 1.7

 

−0.5 ± 1.5

*

0.015

*

Picture completion

0.7 ± 2.0

*

0.9 ± 2.1

*

0.753

 

Coding

−0.4 ± 3.0

 

0.4 ± 2.3

 

0.093

 

Picture arrangement

0.5 ± 1.7

 

1.0 ± 2.0

**

0.254

 

Block design

0.3 ± 2.1

 

0.2 ± 1.9

 

0.962

 

Object assembly

1.2 ± 2.0

**

0.2 ± 2.1

 

0.048

*

Digit span

0.7 ± 2.0

 

0.5 ± 1.9

 

0.770

 

Symbol search

−1.1 ± 2.8

 

−0.2 ± 1.7

 

0.190

 

FIQ

3.6 ± 7.0

**

2.3 ± 7.8

*

0.367

 

VIQ

2.6 ± 8.5

 

0.8 ± 5.7

 

0.280

 

PIQ

2.8 ± 8.8

 

4.9 ± 9.2

**

0.315

 

VCI

2.2 ± 6.3

 

−0.5 ± 5.8

 

0.066

 

POI

3.4 ± 7.6

*

3.4 ± 7.2

**

0.992

 

FDI

0.3 ± 6.6

 

1.4 ± 7.0

 

0.616

 

PSI

−1.3 ± 11.8

 

1.1 ± 7.8

 

0.421

 
  1. 1by paired t-test; 2P value by 2 sample t-test.
  2. *: <0.05, **: <0.01 and ***: <0.001.