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Table 5 Use of LAI FGA and LAI SGA according to the period of the illness

From: Guidelines for the use and management of long-acting injectable antipsychotics in serious mental illness

LAI FGA

LAI SGA

Schizophrenia

LAI FGA are not recommended in the initial phase of the disorder.

Very early introduction of LAI SGA is recommended (eventually from the 1st psychotic episode).

LAI FGA can be used during the maintenance treatment in the case of the efficacy of the oral form and when the benefit/risk ratio is considered as satisfactory.

It is recommended that an LAI SGA be introduced from the 1st recurrent psychotic episode (if the patient was not treated with an LAI antipsychotic).

Bipolar disorder

LAI FGA are not recommended.

LAI SGA are not recommended in the initial phase of bipolar disorder.