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Table 8 Benefit/risk ratio for LAI FGA and LAI SGA in bipolar disorder

From: Guidelines for the use and management of long-acting injectable antipsychotics in serious mental illness

 

Prevention of manic recurrence

Prevention of depressive recurrence

1 st -line treatment

-

-

2 nd -line treatment

In monotherapy or in combination with a mood stabilizer

Always in combination with a mood stabilizer

Risperidone LAI

Risperidone LAI

Olanzapine pamoate

Olanzapine pamoate