Table 1 Definitions and criteria for post hoc analysis of clinical response and symptomatic remission[12, 18]
Terms | Definitions and Criteria |
|---|---|
Clinical response | ≥30% reduction in ADHD-RS-IV with adult prompts total scorea and a CGI-I rating of 1 or 2 |
Symptomatic remission | ADHD-RS-IV total score ≤18 (average per-item score ≤1) |
Time to median clinical response or symptomatic remission | Time by which half the original sample achieves criteria for clinical response or symptomatic remission |
Loss of clinical response or symptomatic remission status | Failure to meet criteria for clinical response or symptomatic remission after having achieved that status at a previous visit |
Maintenance of clinical response or symptomatic remission at endpoint | 4-week trial: |
Participants meeting criteria for clinical response or symptomatic remission at postbaseline visits, enrolled at endpoint, and meeting criteria without interruption | |
Long-term trial: | |
Participants meeting criteria for clinical response or symptomatic remission at postbaseline visits and meeting the criteria without interruption up to endpoint |